Results 101 to 110 of about 7,148,473 (289)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
NCRM podcast: Narrative imagination and everyday life
, 2013 From the challenge of envisioning our own futures to the storytelling skills of Barack Obama, a new book from the Professor Molly Andrews (NOVELLA node) explores how the links between stories and imagination affect the way we live.
Andrews, Molly
core +1 more source
European Journal of PsychotraumatologyIntroduction: Postmigration stress has been recognised as a significant factor negatively impacting the psychological well-being of forcibly displaced people (FDP), even independently of pre-migration trauma exposure.
Rojan Amini-Nejad +2 more
doaj +1 more source
Argument Pedagogy for Everyday Life
Journal of Communication Pedagogy, 2019 This article assists argumentation and debate instructors in developing courses that provide coverage of foundational concepts while reflecting their own interests.
Jeffrey P. Mehltretter Drury +2 more
doaj +1 more source
Moral Punishment in Everyday Life
Personality and Social Psychology Bulletin, 2018 The present research investigated event-related, contextual, demographic, and dispositional predictors of the desire to punish perpetrators of immoral deeds in daily life, as well as connections among the desire to punish, moral emotions, and momentary well-being.
Wilhelm Hofmann +4 more
openaire +4 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Life after stroke: Reconstructing everyday life [PDF]
, 2003 Stroke can have a major impact on a person’s life. For example a stroke may leave an individual with residual disabilities such as difficulty with walking or speech that creates considerable challenges to everyday life.
Alaszewski, Helen P. +4 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Everyday life information experiences in Twitter: a grounded theory
, 2019 Introduction. This paper presents the findings from a project that investigated people's everyday life information experiences on Twitter. Method. The project employed constructivist grounded theory methodology, which emphasizes personal, subjective ...
Miller, Faye +2 more
core +1 more source