Results 141 to 150 of about 1,940,060 (340)

FREE JOURNALISTS COLLECTIVE:
independence affirmed in everyday life

open access: diamond, 2020
Adilson Vaz Cabral Filho   +1 more
openalex   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Toronto’s Smart City: Everyday Life or Google Life?

open access: yesArchitecture_MPS, 2019
In August 2015, Google reorganized its various interests as a conglomerate called Alphabet Inc. Under the new umbrella, Google’s search, data aggregation, and advertising subsidiaries, were joined by Sidewalk Lab and its suite of urban products: high ...
doaj   +2 more sources

Everyday life and mastocytosis from a patient perspective—a qualitative study [PDF]

open access: bronze, 2018
Britt Jensen   +3 more
openalex   +1 more source

Negotiating cultural difference in everyday life : some insights for inclusionary local governance

open access: yes, 2009
With the waning of state-sponsored multiculturalism, local governments in Australia have assumed leadership and responsibility for establishing and maintaining collaborative relationships with stakeholders to promote diverse and inclusive cities ...
Lobo, Michele
core  

Using History to Study Information Seeking Behavior [PDF]

open access: yes, 2010
has focused on approaches that provide a snapshot in time of what is going on in a household. This poster explores the use of history to examine changes over time in both information questions and information sources used in the prosecution of ...
Aspray, William, Hayes, Barbara
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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