Results 251 to 260 of about 32,744,920 (289)

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Teaching evidence-based medicine in medical education: data on barriers and requirements in non-university and university hospitals. [PDF]

open access: yesBMC Med Educ
Luchsinger L   +6 more
europepmc   +1 more source

Adoption of evidence-based medicine: A comparative study of hospital and community pharmacists in Saudi Arabia. [PDF]

open access: yesPLoS One
Alzahrani F   +8 more
europepmc   +1 more source

Evidence-based medicine

Seminars in Perinatology, 1997
Evidence-based medicine, whose philosophical origins extend back to mid-19th century Paris and earlier, is the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients. The practice of evidence-based medicine means integrating individual clinical expertise with the best available ...
F, Porzsolt, R, Kunz
  +11 more sources

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