Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Assessment of knowledge, attitudes, practices, and self-efficacy toward evidence-based medicine among resident physicians: a cross-sectional study from Qatar. [PDF]
Mohammed Ahmed W +3 more
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Evidence-Based Medicine: <i>Knowledge, attitudes and practices among senior medical students and interns in Oman</i>. [PDF]
Al-Hadhrami RS +3 more
europepmc +1 more source
GLP-1 receptor agonist for weight loss and fertility: Social media and online perception versus evidence-based medicine. [PDF]
Merhi Z, Karekar M, Mouanness M.
europepmc +1 more source
The impact of evidence-based medicine curricula on information literacy among clinical medical undergraduates and postgraduates in China. [PDF]
Wang C, Yao Y, Chen Y, Chen J.
europepmc +1 more source
"I still have not mastered that skill!" Medical student perspectives on a simulation-based evidence-based medicine competency assessment. [PDF]
Nicholson J +5 more
europepmc +1 more source
Reevaluating Mask Effectiveness: Insights From Evidence-Based Medicine and Clinical Trials. [PDF]
Spira B.
europepmc +1 more source
Development of a Japanese version of the Fresno test for family physicians to measure evidence-based medicine competence. [PDF]
Kataoka Y +5 more
europepmc +1 more source

