Results 271 to 280 of about 4,993,323 (339)

Evidence-based medicine e linee guida di pratica clinica: soluzione o parte del problema?

, 2001
Angelo Bignamini
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

"I still have not mastered that skill!" Medical student perspectives on a simulation-based evidence-based medicine competency assessment. [PDF]

J Med Libr Assoc
Nicholson J, Plovnick C, Magro J, van der Vleuten C, de Bruin A, Kalet A.   +5 more
europepmc   +1 more source

The Sound of Medicine : Evidence-based music interventions in healthcare practice

, 2019
A. Y. Rosalie Kühlmann
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines. [PDF]

Wideochir Inne Tech Maloinwazyjne
Szeliga J, Jagielski M, Sobocki J, Borys M, Czuczwar M, Durczyński A, Gach T, Hogendorf P, Kawiński A, Kuśnierz K, Major P, Mik M, Pędziwiatr M, Piwowarczyk P, Sierżęga M, Spychalski M, Szczeklik W, Szura M, Wierdak M, Zgodziński W, Budzyński A, Hać S, Jackowski M, Kielan W, Kukla M, Mrowiec S, Myśliwiec P, Sieńko J, Słodkowski M, Tarnowski W, Wallner G, Zawadzki M, Zieniewicz K.   +32 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Reevaluating Mask Effectiveness: Insights From Evidence-Based Medicine and Clinical Trials. [PDF]

Cureus
Spira B.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

[Medical Practice, Epidemiology, and Evidence-Based Medicine: A necessary triangle in healthcare]. [PDF]

Rev Med Inst Mex Seguro Soc
Vallejos-Parás A, Cabrera-Gaytán DA, Hernández-Bautista PF, Jaimes-Betancourt L, Cruz-Orozco O, Valle-Alvarado G.   +5 more
europepmc   +1 more source