Results 271 to 280 of about 6,749,585 (382)

Evidence-based medicine: The new paradigm of clinical decision making

, 2000
Santosh Kumar
openalex   +1 more source

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

"I still have not mastered that skill!" Medical student perspectives on a simulation-based evidence-based medicine competency assessment. [PDF]

J Med Libr Assoc
Nicholson J, Plovnick C, Magro J, van der Vleuten C, de Bruin A, Kalet A.   +5 more
europepmc   +1 more source

Evidence-based medicine training in internal medicine residency programs

, 2000
Michael L. Green
openalex   +2 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines. [PDF]

Wideochir Inne Tech Maloinwazyjne
Szeliga J, Jagielski M, Sobocki J, Borys M, Czuczwar M, Durczyński A, Gach T, Hogendorf P, Kawiński A, Kuśnierz K, Major P, Mik M, Pędziwiatr M, Piwowarczyk P, Sierżęga M, Spychalski M, Szczeklik W, Szura M, Wierdak M, Zgodziński W, Budzyński A, Hać S, Jackowski M, Kielan W, Kukla M, Mrowiec S, Myśliwiec P, Sieńko J, Słodkowski M, Tarnowski W, Wallner G, Zawadzki M, Zieniewicz K.   +32 more
europepmc   +1 more source

Failure of evidence-based medicine in the treatment of hypertension in older patients

, 2000
Eric L. Knight, Robert J. Glynn, Raisa Levin, David A. Ganz, Jerry Avorn   +4 more
openalex   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Reevaluating Mask Effectiveness: Insights From Evidence-Based Medicine and Clinical Trials. [PDF]

Cureus
Spira B.
europepmc   +1 more source

Effect of an Evidence-based Medicine Seminar on Participantsʼ Interpretations of Clinical Trials

, 2000
Philip Schoenfeld, David Cruess, William Peterson   +2 more
openalex   +1 more source