Results 41 to 50 of about 2,390,694 (316)
Ethics for Digital Medicine: A Path for Ethical Emerging Medical IoT Design [PDF]
arXiv, 2022 The dawn of the digital medicine era, ushered in by increasingly powerful embedded systems and Internet of Things (IoT) computing devices, is creating new therapies and biomedical solutions that promise to positively transform our quality of life. However, the digital medicine revolution also creates unforeseen and complex ethical, regulatory, and ...
arxiv
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
BMC Medical Research MethodologyIntroduction Interrupted time series (ITS) design is a commonly used method for evaluating large-scale interventions in clinical practice or public health. However, improperly using this method can lead to biased results.
Yuanjin Zhang +9 more
doaj +1 more source
Emerging photodynamic/sonodynamic therapies for urological cancers: progress and challenges
Journal of Nanobiotechnology, 2022 Photodynamic therapy (PDT), and sonodynamic therapy (SDT) that developed from PDT, have been studied for decades to treat solid tumors. Compared with other deep tumors, the accessibility of urological tumors (e.g., bladder tumor and prostate tumor) makes
Xiao Hu +5 more
doaj +1 more source
Past, present and future of living systematic review: a bibliometrics analysis
BMJ Global Health, 2022 Introduction In recent years, the concept of living systematic review (LSR) has attracted the attention of many scholars and institutions. A growing number of studies have been conducted based on LSR methodology, but their focus direction is unclear. The
Jinhui Tian +12 more
doaj +1 more source
Integrative AI-Driven Strategies for Advancing Precision Medicine in Infectious Diseases and Beyond: A Novel Multidisciplinary Approach [PDF]
arXiv, 2023 Precision medicine, tailored to individual patients based on their genetics, environment, and lifestyle, shows promise in managing complex diseases like infections. Integrating artificial intelligence (AI) into precision medicine can revolutionize disease management.
arxiv
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Journal of the Royal Society of Medicine, 2008 Duncan Neuhauser, Mireya Diaz and Iain Chalmers (JRSM 2008;101:381–383) are puzzled that one of the great pioneers of clinical trials, Russell LaFayette Cecil, failed to include a chapter on trial methodology when he went on to edit his best-selling Textbook of Medicine – but perhaps they are being diplomatic.1 If Cecil thought most doctors did not ...
openaire +4 more sources
PROSPERO's systematic review protocols of traditional Chinese medicine for COVID-19: An overview
Integrative Medicine Research, 2021 Background: A large number of protocols for Systematic Reviews (SR) of Traditional Chinese Medicine (TCM) for coronavirus disease 2019 (COVID-19) have been registered in the International Prospective Register of Systematic Reviews (PROSPERO).
Haiyin Hu +6 more
doaj
Frontiers in Pharmacology, 2021 Objective: To present the evidence of the therapeutic effects and safety of Chinese herbal medicine (CHM) used with or without conventional western therapy for COVID-19.Methods: Clinical studies on the therapeutic effects and safety of CHM for COVID-19 ...
Shi-Bing Liang +16 more
doaj +1 more source