Results 61 to 70 of about 3,253,570 (293)

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Design and statistical analysis reporting among interrupted time series studies in drug utilization research: a cross-sectional survey

BMC Medical Research Methodology
Introduction Interrupted time series (ITS) design is a commonly used method for evaluating large-scale interventions in clinical practice or public health. However, improperly using this method can lead to biased results.
Yuanjin Zhang, Yan Ren, Yunxiang Huang, Minghong Yao, Yulong Jia, Yuning Wang, Fan Mei, Kang Zou, Jing Tan, Xin Sun   +9 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Characteristics and recovery methods of studies falsely excluded during literature screening—a systematic review

Systematic Reviews, 2022
Background Due to the growing need to provide evidence syntheses under time constraints, researchers have begun focusing on the exploration of rapid review methods, which often employ single-reviewer literature screening.
Lisa Affengruber, Andreea Dobrescu, Emma Persad, Irma Klerings, Gernot Wagner, Isolde Sommer, Gerald Gartlehner   +6 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Improving the health of the population and evidence based medicine [PDF]

, 2010
This is a module framework. It can be viewed online or downloaded as a zip file. As taught in Autumn Semester 2009 This module has two essential components: Evidence-Based Medicine and Public Health.
Myles Puja R. Dr
core  

The Philosophy of Evidence-Based Medicine [PDF]

, 2011
Evidence-based medicine (EBM) has become a required element of clinical practice, but it is critical for the healthcare community to understand the ongoing controversy surrounding EBM.
Howick, Jeremy, Jeremy Howick, howick,jeremy, Howick, J   +3 more
core   +1 more source

Identifying, handling and impact of immortal time bias on addressing treatment effects in observational studies using routinely collected data

BMC Medical Research Methodology
Background Immortal time bias (ITB) represents a methodological challenge in evaluating treatment effects in observational studies using routinely collected data (RCD).
Shuangyi Xie, Jiayue Xu, Qiao He, Yuning Wang, Qianrui Li, Xia Zhang, Yunxiang Huang, Yuanjin Zhang, Wen Wang, Xin Sun   +9 more
doaj   +1 more source

Acupuncture for ulcerative colitis: a systematic review and meta-analysis of randomized clinical trials

BMC Complementary Medicine and Therapies, 2020
Background Ulcerative colitis, characterized by diarrhea, bloody stools and abdominal pain, is a chronic, idiopathic inflammatory disease of the colonic mucosa.
Xiao Wang, Nan-qi Zhao, Yu-xin Sun, Xue Bai, Jiang-tao Si, Jian-ping Liu, Zhao-lan Liu   +6 more
doaj   +1 more source

The effect of e-cigarettes on smoking cessation and cigarette smoking initiation: An evidence-based rapid review and meta-analysis

Tobacco Induced Diseases, 2021
Introduction The contribution made by e-cigarettes to smoking cessation continues to be controversial. Reports suggest that teenagers are becoming increasingly addicted to e-cigarettes and that e-cigarette use in adolescents is associated with subsequent
Ying-Ying Zhang, Fan-Long Bu, Fei Dong, Jian-Hua Wang, Si-Jia Zhu, Xiao-Wen Zhang, Nicola Robinson, Jian-Ping Liu   +7 more
doaj   +1 more source