Results 61 to 70 of about 32,744,920 (289)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Past, present and future of living systematic review: a bibliometrics analysis

BMJ Global Health, 2022
Introduction In recent years, the concept of living systematic review (LSR) has attracted the attention of many scholars and institutions. A growing number of studies have been conducted based on LSR methodology, but their focus direction is unclear. The
Jinhui Tian, Ming Liu, Junhua Zhang, Jie Cheng, Jianguo Xu, Ya Gao, Qingyong Zheng, Luying Cheng, Lu Xiong, Mengyuan Yuan, Guoyuan OuYang, Hengyi Huang, Jiarui Wu   +12 more
doaj   +1 more source

The Nature of Evidence in Evidence-Based Medicine [PDF]

, 2009
The article focuses on the examination of evidence-based medicine (EBM) in medicine. EBM's contribution in the clinical practice has long been used in the development of institutional and professional guidelines in health promotion and other ...
Borgerson, Kirstin, Goldenberg, Maya J., Bluhm, Robyn   +2 more
core   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Identifying, handling and impact of immortal time bias on addressing treatment effects in observational studies using routinely collected data

BMC Medical Research Methodology
Background Immortal time bias (ITB) represents a methodological challenge in evaluating treatment effects in observational studies using routinely collected data (RCD).
Shuangyi Xie, Jiayue Xu, Qiao He, Yuning Wang, Qianrui Li, Xia Zhang, Yunxiang Huang, Yuanjin Zhang, Wen Wang, Xin Sun   +9 more
doaj   +1 more source

Acupuncture for ulcerative colitis: a systematic review and meta-analysis of randomized clinical trials

BMC Complementary Medicine and Therapies, 2020
Background Ulcerative colitis, characterized by diarrhea, bloody stools and abdominal pain, is a chronic, idiopathic inflammatory disease of the colonic mucosa.
Xiao Wang, Nan-qi Zhao, Yu-xin Sun, Xue Bai, Jiang-tao Si, Jian-ping Liu, Zhao-lan Liu   +6 more
doaj   +1 more source

Evidence-Based Medicine

Keyes D, Varacallo MA.
europepmc   +2 more sources

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Design and statistical analysis reporting among interrupted time series studies in drug utilization research: a cross-sectional survey

BMC Medical Research Methodology
Introduction Interrupted time series (ITS) design is a commonly used method for evaluating large-scale interventions in clinical practice or public health. However, improperly using this method can lead to biased results.
Yuanjin Zhang, Yan Ren, Yunxiang Huang, Minghong Yao, Yulong Jia, Yuning Wang, Fan Mei, Kang Zou, Jing Tan, Xin Sun   +9 more
doaj   +1 more source

Cupping therapy versus acupuncture for pain-related conditions: a systematic review of randomized controlled trials and trial sequential analysis

Chinese Medicine, 2017
Background Both cupping therapy and acupuncture have been used in China for a long time, and their target indications are pain-related conditions. There is no systematic review comparing the effectiveness of these two therapies. Objectives To compare the
Ya-Jing Zhang, Hui-Juan Cao, Xin-Lin Li, Xiao-Ying Yang, Bao-Yong Lai, Guo-Yang Yang, Jian-Ping Liu   +6 more
doaj   +1 more source