Results 71 to 80 of about 3,253,570 (293)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

Narrative based medicine: narrative based medicine in an evidence based world [PDF]

open access: yes, 1999
Summary points: Even "evidence based" clinicians uphold the importance of clinical expertise and judgment. Clinical method is an interpretive act which draws on narrative skills to integrate the overlapping stories told by patients, clinicians, and test ...
Greenhalgh, T.   +3 more
core   +1 more source

Neutrophil-to-albumin ratio as a predictor of mortality in patients with intracerebral hemorrhage: a multicenter retrospective cohort study

open access: yesBMC Neurology
Background Intracerebral hemorrhage (ICH) is associated with a poor prognosis. The association between the neutrophil-to-albumin ratio (NAR) with mortality in patients with ICH remains underexplored.
Jun Wan   +11 more
doaj   +1 more source

Cupping therapy versus acupuncture for pain-related conditions: a systematic review of randomized controlled trials and trial sequential analysis

open access: yesChinese Medicine, 2017
Background Both cupping therapy and acupuncture have been used in China for a long time, and their target indications are pain-related conditions. There is no systematic review comparing the effectiveness of these two therapies. Objectives To compare the
Ya-Jing Zhang   +6 more
doaj   +1 more source

Academic medicine: the evidence base [PDF]

open access: yesBMJ, 2004
The International Campaign to Revitalise Academic Medicine recognises that an evidence based approach is important in discussing the problems of academic medicine. A preliminary exploration of the evidence on academic medicine has led to a research agenda for examining and proposing realistic solutions. Copyright © 2004, BMJ Publishing Group Ltd.
Ioannidis, J. P. A.   +14 more
openaire   +5 more sources

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot   +6 more
wiley   +1 more source

Application of patient-reported outcomes in clinical trials of traditional Chinese medicine registered in international clinical trials registry platform, from 2010 to 2022: a cross-sectional study

open access: yesJournal of Patient-Reported Outcomes
Purpose Patient-reported outcomes (PROs) assist patients and clinicians in assessing treatment effectiveness and enhancing healthcare quality. This study aims to explore and analyze the application and characteristics of PROs in clinical trials of ...
Yuanyuan Lin   +10 more
doaj   +1 more source

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark   +9 more
wiley   +1 more source

Evidence‐based medicine as science [PDF]

open access: yesJournal of Evaluation in Clinical Practice, 2018
AbstractEvidence‐based medicine has claimed to be science on a number of occasions, but it is not clear that this status is deserved. Within the philosophy of science, four main theories about the nature of science are historically recognized: inductivism, falsificationism, Kuhnian paradigms, and research programmes.
Vere, J., Gibson, B.J.
openaire   +3 more sources

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