Results 71 to 80 of about 5,020,592 (244)

Contexts of diffusion: Adoption of research synthesis in Social Work and Women's Studies

, 2014
Texts reveal the subjects of interest in research fields, and the values, beliefs, and practices of researchers. In this study, texts are examined through bibliometric mapping and topic modeling to provide a birds eye view of the social dynamics ...
A. Abbott, A. Asuncion, A. Stirling, D.M. Blei, Evidence-Based Medicine Working Group, I. Chalmers, I. Rafols, I. Rafols, J.T. Klein, J.W. Anastas, L. Toews, L.V. Hedges, M. Herie, M.J. Boxer, V. Batagelj   +14 more
core   +1 more source

Bad news: analysis of the quality of information on influenza prevention returned by Google in English and Italian [PDF]

, 2015
Information available to the public influences the approach of the population toward vaccination against influenza compared with other preventative approaches.
Allam, Alves Galvao, Ballou, Bartlett, Berland, Bernstam, Briggs, Chumber, Crocco, Cutrell, Davies, Dy, Evidence-Based Medicine Working Group, Fabricant, Fabry, Fox, Ghezzi, Granka, Guppy, Hemila, Hemila, Jefferson, Jefferson, Jefferson, Jefferson, Kilgarriff, Lehmann, Mathie, Mazanderani, McRee, Meric, Nasir, Pauling, Price, Silberg, Sillence, Wand, Yaqub, Zeldman   +38 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Clinical decision making:Surgical management of left displaced abomasum in dairy cattle [PDF]

, 2016
Critically Appraised Topics (CATs) are a standardised, succinct summary of research evidence organised around a clinical question, using a form of evidence synthesis based on the principles of evidence-based medicine (EBM) and evidence-based veterinary ...
Barrett, David C, Boocock, Jennifer, Dickinson, Matthew, Johnson, Claire, Mitchell, Thomas, Place, Emma J, Rees, Gwen M, Reyher, Kristen K   +7 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Evidence‐based medicine [PDF]

Equine Veterinary Journal, 2020
openaire   +4 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Traditional Chinese Medicine and Its Role in Women’s Health [PDF]

, 2020
This paper is a literature review of traditional Chinese medicine and its role in women’s health. A search was performed and a group of 208 articles were initially found using the Liberty Summons search engine.
Smith, Ezekiel
core   +1 more source