Results 91 to 100 of about 3,253,570 (293)

How fragile the positive results of Chinese herbal medicine randomized controlled trials on irritable bowel syndrome are?

BMC Complementary Medicine and Therapies
Objective The fragility index (FI), which is the minimum number of changes in status from “event” to “non-event” resulting in a loss of statistical significance, serves as a significant supplementary indicator for clinical physicians in interpreting ...
Minjing Luo, Jinghan Huang, Yingqiao Wang, Yilin Li, Zhihan Liu, Meijun Liu, Yunci Tao, Rui Cao, Qianyun Chai, Jianping Liu, Yutong Fei   +10 more
doaj   +1 more source

Evidence-based occupational health and safety interventions: a comprehensive overview of reviews

BMJ Open, 2019
Objectives Occupational injuries and diseases are a huge public health problem and cause extensive suffering and loss of productivity. Nevertheless, many occupational health and safety (OHS) guidelines are still not based on the best available evidence ...
Birgit Teufer, Irma Klerings, Lisa Affengruber, Agnes Ebenberger, Christina Kien, Monika Szelag, Ludwig Grillich, Ursula Griebler   +7 more
doaj   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source

"Evidence-Debased Medicine" and the Integrity of the Medical Profession [PDF]

, 2011
Patients trust physicians to prescribe based on their fiduciary duty to act in the best interests of their patients, and physicians prescribe based on confidence in research data and clinical guidelines.
Elliott, Richard L
core  

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

Chinese Herbal Medicine as Adjunctive Therapy to Chemotherapy for Breast Cancer : A Systematic Review and Meta-Analysis [PDF]

, 2016
Chinese herbal medicine (CHM) has been increasingly employed during therapy for breast cancer, but its efficacy remains a matter of debate. This systematic review examined randomized controlled trials to provide a critical evaluation of this treatment ...
Nian, Jia-Yun,, Zhang, Xing, Nian, Jia-Yun, Yu, Ming-Wei,, Yang, Guo-Wang,, Yu, Ming-Wei, Zhang, Yi, Zhang, Xing,, Cheng, Pei-Yu,, Guo, Jiao, Sun, Xu, Li, Jin-Ping, Wang, Xiao-Min,, Zhang, Gan-Lin, Zhang, Yi,, Wang, Xiao-Min, Yang, Guo-Wang, Cheng, Pei-Yu, Sun, Xu,, Yang, Lin,, Yin, Yi,, Guo, Jiao,, Yang, Lin, Yin, Yi, Zhang, Gan-Lin,, Li, Jin-Ping,   +25 more
core   +1 more source

Effects of SGLT2 inhibitors on UTIs and genital infections in type 2 diabetes mellitus: a systematic review and meta-analysis

Scientific Reports, 2017
Previous trial evidence suggested potential risk of serious urinary tract infections (UTIs) and genital infections in type 2 diabetes patients using sodium glucose co-transporter-2 inhibitors (SGLT2) inhibitors.
Jiali Liu, Ling Li, Sheyu Li, Pengli Jia, Ke Deng, Wenwen Chen, Xin Sun   +6 more
doaj   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

PICC超声引导下肘上置管的穿刺置管效果及并发症的系统评价 [PDF]

, 2013
Objective 　To systematically evaluate the influence of PICC (peripherally inserted central catheter) ultrasound guidance on success rates and incidences of complications of elbow catheterization.Methods 　The Cochrane Library (Issue 3, 2012), Library of ...
Lu, Zhenqi, Li, Quanlei, Yan, Meiqiong, Zhang, Xiaoju, Lin, Cen   +4 more
core   +1 more source

Clinical anatomy of distal femur and its implications in total knee arthroplasty: a radiological study

Journal of Orthopaedic Surgery and Research
Background Osteoarthritis (OA) of the knee is a chronic disease affecting joints and its tissues, leading to gradual damage of articular cartilage and surrounding synovial tissues.
Jakub Pękala, Monika Stępień, Jonasz Tempski, Maciej Jędrychowski, Jędrzej Bartoszcze, Konrad Malinowski, Przemysław Pękala, Tadeusz Popiela, Jerzy Walocha   +8 more
doaj   +1 more source