Results 111 to 120 of about 32,744,920 (289)

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Medical scientists and philosophers worldwide appeal to EBM to expand the notion of ‘evidence’ [PDF]

, 2018
The rapid dominance of evidence-based medicine has sparked a philosophical debate concerning the concept of evidence. We urge that evidence-based medicine, if it is to be practised in accordance with its own mandate, should also acknowledge the ...
Copeland, Samantha Marie, Rocca, Elena, Rocca, E. (author), Copeland, S.M. (author), Anjum, Rani Lill, Anjum, R.L. (author)   +5 more
core   +1 more source

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

Corroborating evidence‐based medicine [PDF]

Journal of Evaluation in Clinical Practice, 2014
AbstractProponents of evidence‐based medicine (EBM) have argued convincingly for applying this scientific method to medicine. However, the current methodological framework of the EBM movement has recently been called into question, especially in epidemiology and the philosophy of science.
openaire   +4 more sources

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

A Randomized, Sham-Controlled Trial on the Efficacy and Safety of Electroacupuncture for Lumbar Disc Herniation with Radiculopathy: Rationale and Study Protocol

Journal of Pain Research
Yuwei Yang,1,* Liting Liu,1,* Lixia Yuan,1 Xiaoya Liu,1 Haoying Ding,2 Xu Zhou,3 Qianan Cao4 1Graduate School, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, 330004, People’s Republic of China; 2The First Department of ...
Yang Y, Liu L, Yuan L, Liu X, Ding H, Zhou X, Cao Q   +6 more
doaj  

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Phase-engineered MoS2 nanosheets/probiotic vesicles hydrogel for diabetic wound healing via dynamic ROS modulation

Journal of Nanobiotechnology
Diabetic wound repair remains a huge clinical challenge and drives demand for advanced therapies. Most novel nanomaterial-based dressings exploit elevated reactive oxygen species (ROS) for antibacterial efficacy are short of the intelligent of ROS ...
Yu-Sen Zhang, Shuai Ke, Jia Zhang, Meng Luo, Bing-Hui Li, Xing-Xian Liu, Zhi-Jun Lu, Ruo-Fei Liu, Xian-Tao Zeng, Ling-Ling Zhang   +9 more
doaj   +1 more source

Ethics and evidence based medicine

BMJ, 1998
Evidence based medicine is founded upon an ideal—that decisions about the care of individual patients should involve the “conscientious, explicit and judicious use of current best evidence.”1 Several publications are dedicated to evidence based medicine, and, at an international level, the Cochrane Collaboration has been formed to gather, analyse, and ...
Kerridge, I, Lowe, M, Henry, D
openaire   +5 more sources

Global health: the importance of evidence-based medicine [PDF]

, 2013
Global health is a varied field that comprises research, evaluation and policy that, by its definition, also occurs in disparate locations across the world.
Zhou, Xiao-Nong, Wiysonge, Charles S., Frenk, Julio J., Mills, Edward J, Birbeck, Gretchen L., Mills, Edward J., Wiysonge, Charles S, Frenk, Julio J, Birbeck, Gretchen L, Jha, Prabhat, Edward J Mills, Gretchen L Birbeck, Julio J Frenk, Charles S Wiysonge, Prabhat Jha, Xiao-Nong Zhou   +15 more
core   +2 more sources