Results 111 to 120 of about 5,740,750 (360)

Practice, complexity and evidence-based practice [PDF]

British Dental Journal, 2019
In this opinion piece, I explore practice and complexity, the latter a term often used in relation to the field of special care dentistry. As research is usually concerned with generating new knowledge of some sort, I explore how knowledge is viewed from a practice perspective, as shared, transitory and situated in interactions, rather than being a ...
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

123 Methods for determining the conclusiveness of systematic review results: A living scoping review

Journal of Clinical and Translational Science
Objectives/Goals: Understanding systematic review results help prioritise more valuable studies. However, evaluating whether a systematic review has conclusively answered a question is difficult, and it is unclear which tools are available for such ...
Troels Madsen, Karen Robinson, Hans Lund, Jong-Wook Ban   +3 more
doaj   +1 more source

Integrating Evidence-based Teaching and Learning Practices into the Core Engineering Curriculum: Student Perceptions of the Instructional Practices [PDF]

, 2020
Gail P. Baxter, Keith Sheppard, Frank T. Fisher, Patricia J. Holahan, Susan Lowes, Susan Metz   +5 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The OneTogether collaborative approach to reduce the risk of surgical site infection: identifying the challenges to assuring best practice [PDF]

, 2015
Background: Surgical site infections (SSI) account for 16% of healthcare associated infections, and are associated with considerable morbidity, mortality and increased costs of care.
Gallagher, Rose, Neachell, Jonathan, Stott, Dawn, Topley, Katherine, Wilson, Jennie   +4 more
core   +1 more source

A qualitative study of health care professionals’ views and experiences of paediatric advance care planning

BMC Palliative Care, 2018
Background Good end-of-life care planning is vital to ensure optimal care is provided for patients and their families. Two key factors are open and honest advance care planning conversations between the patient (where possible), family, and health care ...
Barbara A. Jack, Tracy K. Mitchell, Mary R. O’Brien, Sergio A. Silverio, Katherine Knighting   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Engaging Nursing Staff in Research: The Clinical Nurse Specialist Role in an Academic-Clinical Partnership [PDF]

, 2016
Purpose: The purpose of this article is to describe the processes of exploring and implementing an academic-clinical study, engaging nursing staff in research, and maintaining their enthusiasm within the context of an academic-clinical research ...
Boaz, Lesley, Bull, Margaret J., Gettrust, Lynn, Hagle, Mary E.   +3 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source