Results 1 to 10 of about 715,855 (318)

Mapping and systematic appraisal of umbrella reviews in epidemiological research: a protocol for a meta-epidemiological study [PDF]

open access: yes, 2023
Introduction: Umbrella review is one of the terms used to describe an overview of systematic reviews. During the last years, a rapid increase in the number of umbrella reviews on epidemiological studies has been observed, but there is no systematic ...
Lazaros Belbasis   +17 more
core   +1 more source

The problems with systematic reviews: a living systematic review

open access: yesJournal of Clinical Epidemiology, 2023
Systematic reviews and meta-analyses are proliferating as they are an important building block to inform evidence-based guidelines and decision-making. Enforcement of best practice in clinical trials is firmly on the research agenda of good clinical practice, but there is less clarity as to how evidence syntheses that combine these studies can be ...
Uttley, L.   +7 more
openaire   +3 more sources

Exponential growth of systematic reviews assessing artificial intelligence studies in medicine: challenges and opportunities [PDF]

open access: yes, 2022
The evidence-based medicine (EBM) movement is stepping up its efforts to assess medical artificial intelligence (AI) and data science studies. Since 2017, there has been a marked increase in the number of published systematic reviews that assess medical ...
Puljak, Livia   +10 more
core   +1 more source

High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation

open access: yesHealth Technology Assessment, 2021
Background: Early diagnosis of acute myocardial infarction is important, but only 20% of emergency admissions for chest pain will actually have an acute myocardial infarction.
Marie Westwood   +9 more
doaj   +1 more source

A Systematic Review of Systematic Reviews of Spinal Manipulation [PDF]

open access: yesJournal of the Royal Society of Medicine, 2006
Objectives To systematically collate and evaluate the evidence from recent systematic reviews of clinical trials of spinal manipulation. Design Literature searches were carried out in four electronic databases for all systematic ...
E, Ernst, P H, Canter
openaire   +2 more sources

A systematic review of clinical effectiveness and safety for historical and current treatment options for metachromatic leukodystrophy in children, including atidarsagene autotemcel

open access: yesOrphanet Journal of Rare Diseases, 2023
Objective To understand the benefit-risk profile for historical and current treatments for MLD. Methods A systematic review was conducted on the effectiveness, safety, and costs of MLD treatments: allogeneic haematopoietic stem cell transplantation (HSCT)
Nigel Armstrong   +3 more
doaj   +1 more source

Accuracy and effectiveness of teledentistry: a systematic review of systematic reviews

open access: yesEvidence-Based Dentistry, 2022
Introduction The COVID-19 pandemic has urged healthcare systems to develop new ways to safely provide care. Telehealth has become a compelling alternative. Our purpose was to evaluate the accuracy and effectiveness of teledentistry for screening, diagnosis and therapeutic management of dental care in children and adults.Methods We conducted a ...
Gurgel-Juarez, Nalia   +8 more
openaire   +2 more sources

Iridoschisis—A Systematic Review [PDF]

open access: yesJournal of Clinical Medicine, 2020
Iridoschisis is a rare condition defined as a separation of the anterior iris stroma from the posterior stroma and muscle layers. In this paper, we review current data about the epidemiology, pathophysiology, clinical characteristics and differential diagnoses of this condition and discuss the specificity of surgical treatment of concomitant ocular ...
Barbara Pieklarz   +5 more
openaire   +3 more sources

Developing critical appraisal of systematic reviews reporting network meta-analysis [PDF]

open access: yes, 2021
The aim of the research presented in this thesis was to advance the critical appraisal of systematic reviews using network meta-analysis (NMA) methods for synthesis.
Lee, Andrew
core   +2 more sources

Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis

open access: yesHealth Technology Assessment, 2020
Background: There have been no licensed treatment options in the UK for treating thrombocytopenia in people with chronic liver disease requiring surgery.
Nigel Armstrong   +15 more
doaj   +1 more source

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