Results 11 to 20 of about 708,426 (318)

The problems with systematic reviews: a living systematic review

Journal of Clinical Epidemiology, 2023
Systematic reviews and meta-analyses are proliferating as they are an important building block to inform evidence-based guidelines and decision-making. Enforcement of best practice in clinical trials is firmly on the research agenda of good clinical practice, but there is less clarity as to how evidence syntheses that combine these studies can be ...
Uttley, L., Quintana, D.S., Montgomery, P., Carroll, C., Page, M.J., Falzon, L., Sutton, A., Moher, D.   +7 more
openaire   +3 more sources

High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation

Health Technology Assessment, 2021
Background: Early diagnosis of acute myocardial infarction is important, but only 20% of emergency admissions for chest pain will actually have an acute myocardial infarction.
Marie Westwood, Bram Ramaekers, Sabine Grimm, Gill Worthy, Debra Fayter, Nigel Armstrong, Titas Buksnys, Janine Ross, Manuela Joore, Jos Kleijnen   +9 more
doaj   +1 more source

A systematic review of clinical effectiveness and safety for historical and current treatment options for metachromatic leukodystrophy in children, including atidarsagene autotemcel

Orphanet Journal of Rare Diseases, 2023
Objective To understand the benefit-risk profile for historical and current treatments for MLD. Methods A systematic review was conducted on the effectiveness, safety, and costs of MLD treatments: allogeneic haematopoietic stem cell transplantation (HSCT)
Nigel Armstrong, Andrew Olaye, Caro Noake, Francis Pang   +3 more
doaj   +1 more source

A Systematic Review of Systematic Reviews of Spinal Manipulation [PDF]

Journal of the Royal Society of Medicine, 2006
Objectives To systematically collate and evaluate the evidence from recent systematic reviews of clinical trials of spinal manipulation. Design Literature searches were carried out in four electronic databases for all systematic ...
E, Ernst, P H, Canter
openaire   +2 more sources

Accuracy and effectiveness of teledentistry: a systematic review of systematic reviews

Evidence-Based Dentistry, 2022
Introduction The COVID-19 pandemic has urged healthcare systems to develop new ways to safely provide care. Telehealth has become a compelling alternative. Our purpose was to evaluate the accuracy and effectiveness of teledentistry for screening, diagnosis and therapeutic management of dental care in children and adults.Methods We conducted a ...
Gurgel-Juarez, Nalia, Torres-Pereira, Cassius, Haddad, Ana E., Sheehy, Lisa, Finestone, Hillel, Mallet, Karen, Wiseman, Michael, Hour, Kannika, Flowers, Heather L.   +8 more
openaire   +2 more sources

Iridoschisis—A Systematic Review [PDF]

Journal of Clinical Medicine, 2020
Iridoschisis is a rare condition defined as a separation of the anterior iris stroma from the posterior stroma and muscle layers. In this paper, we review current data about the epidemiology, pathophysiology, clinical characteristics and differential diagnoses of this condition and discuss the specificity of surgical treatment of concomitant ocular ...
Barbara Pieklarz, Emil Tomasz Grochowski, Emil Saeed, Patryk Sidorczuk, Zofia Mariak, Diana Anna Dmuchowska   +5 more
openaire   +3 more sources

Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis

Health Technology Assessment, 2020
Background: There have been no licensed treatment options in the UK for treating thrombocytopenia in people with chronic liver disease requiring surgery.
Nigel Armstrong, Nasuh Büyükkaramikli, Hannah Penton, Rob Riemsma, Pim Wetzelaer, Vanesa Huertas Carrera, Stephanie Swift, Thea Drachen, Heike Raatz, Steve Ryder, Dhwani Shah, Titas Buksnys, Gill Worthy, Steven Duffy, Maiwenn Al, Jos Kleijnen   +15 more
doaj   +1 more source

Automation of systematic literature reviews: A systematic literature review

Information and Software Technology, 2021
Abstract Context Systematic Literature Review (SLR) studies aim to identify relevant primary papers, extract the required data, analyze, and synthesize results to gain further and broader insight into the investigated domain. Multiple SLR studies have been conducted in several domains, such as software engineering, medicine, and pharmacy. Conducting
Raymon van Dinter, Bedir Tekinerdogan, Cagatay Catal   +2 more
openaire   +4 more sources

Efficacy of antimalarial herbal medicines used by communities in malaria affected regions globally: a protocol for systematic review and evidence and gap map

BMJ Open, 2023
Introduction With the rising resistance to artemisinin-based combination treatments, there is a need to hasten the discovery and development of newer antimalarial agents. Herbal medicines are key for the development of novel drugs.
Nakalembe Loyce, Robert Apunyo, Alison Annet Kinengyere, Moses Ocan, Ekwaro A Obuku, Kevin Ouma Ojiambo   +5 more
doaj   +1 more source

Mapping and systematic appraisal of umbrella reviews in epidemiological research: a protocol for a meta-epidemiological study

, 2023
Introduction: Umbrella review is one of the terms used to describe an overview of systematic reviews. During the last years, a rapid increase in the number of umbrella reviews on epidemiological studies has been observed, but there is no systematic ...
Lazaros Belbasis, John PA Ioannidis, Emmanuel Zavalis, Angelo Maria Pezzullo, Robin D Brooker, Brooker, Robin D., Ioannidis, John P. A., Zavalis, Emmanuel,, Belbasis, Lazaros, Brooker, Robin D.,, Axfors, Cathrine,, Ioannidis, John P. A.,, Cathrine Axfors, Axfors, Cathrine, Zavalis, Emmanuel, Pezzullo, Angelo Maria, Belbasis, Lazaros,, Pezzullo, Angelo Maria,   +17 more
core   +1 more source