Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Translation, cross-cultural adaptation, and validation of the Spanish Evidence-Based Practice Confidence (EPIC) scale in occupational therapy students and professionals [PDF]
Daniel Prieto-Botella +8 more
openalex +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Evidence based practice in postgraduate healthcare education: A systematic review [PDF]
, 2007 Gemma Flores‐Mateo, Josep M. Argimón
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Physical Therapy Clinical Instructor Self-Reported Evidence-Based Practice Use [PDF]
, 2015 Introduction: Evidence-based practice is a required component of student physical therapist education. Practice applying the five steps of evidence-based practice to patient care (formulate question, retrieve evidence, appraise evidence, integrate ...
Bierwas, Debra +4 more
core +1 more source
Toward a Transdisciplinary Model of Evidence‐Based Practice
, 2009 Jason M. Satterfield +6 more
openalex +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Corrigendum to methodological approaches for developing, reporting, and assessing evidence-based clinical practice guidelines: a systematic survey [Journal of Clinical Epidemiology 146 (2022) 77-85] [PDF]
, 2023 Xiaomei Yao +11 more
openalex +1 more source