Results 161 to 170 of about 5,186,936 (309)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Evidence-Based Practice Quality Improvement Reporting Guidelines. [PDF]

open access: yesJ Nurs Care Qual
Reynolds SS, Waldrop JB, Dunlap JJ.
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Integrating clinical data into evidence-based practice: institutional guideline development for diabetic foot infections. [PDF]

open access: yesFront Endocrinol (Lausanne)
Jamil E   +7 more
europepmc   +1 more source

Benefits of a Regional Evidence‐Based Practice Fellowship Program: A Test of the ARCC Model

open access: yesWorldviews on Evidence-Based Nursing, 2017
S. Kim   +5 more
semanticscholar   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Implementation of Evidence-Based Practice Among Respiratory Therapists in Saudi Arabia: A Cross-Sectional Study. [PDF]

open access: yesHealthcare (Basel)
Alahmadi FH   +14 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Successful adoption of an advance care planning evidence-based practice: impact of clinical champion and site factors. [PDF]

open access: yesImplement Sci
Magid KH   +7 more
europepmc   +1 more source

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