Results 171 to 180 of about 5,740,750 (360)

PROTOCOL: Recreational book reading for promoting cognitive functioning and emotional well‐being in older adults: A systematic review

Campbell Systematic Reviews, 2020
Jorien Laermans, Hans Scheers, Philippe Vandekerckhove, Emmy De Buck   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Mentors' attitudes, beliefs and implementation of evidence based practice when mentoring student nurses in the community: a qualitative study [PDF]

Background: Nursing practice based on evidence improves patient care. Mentors supporting student nurses are in clinical placements are in a unique position to demonstrate evidence based practice (EBP).
Brooke, Joanne, Mallion, Jaimee
core  

Midwives' Perceptions of Barriers to Implementing Evidence-Based Practice in Northern Jordan. [PDF]

SAGE Open Nurs
Hatamleh R, Al-Akour N, Smadi R, Atout M.   +3 more
europepmc   +1 more source

Evidence‐based practice supporting primary care prescribing [PDF]

openalex   +1 more source

IMPLEMENTATION OF EVIDENCED-BASED CARE MANAGEMENT PRACTICES AMONG INDEPENDENT PHYSICIAN ASSOCIATIONS SERVING ELDERLY MEDICARE ADVANTAGE AND DUAL ELIGIBLE PROGRAM BENEFICIARIES

, 2020
Jennifer Nora Dunphy
openalex   +1 more source

Evidence-Based Best Practice for Transitions of Care: A Policy Review on Medication Reconciliation Standards

, 2022
Lovelyn Chizoba Ogbennah
openalex   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The Association Between Nursing Work Environment and Evidence-Based Practice. [PDF]

Worldviews Evid Based Nurs
Lana A, Fernández-Arce L, González-García M, Fernández-Iglesias R, Andina-Díaz E, Fernández Feito A.   +5 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source