Results 221 to 230 of about 2,659,136 (310)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Evidence-Based Practice in Dentistry and OMFS: KAP Study.

J Pharm Bioallied Sci
Venugopal T, Khot SN, Tiwari HD, Tiwari R, Shetty A, Musalli R, Managutti AM.   +6 more
europepmc   +1 more source

Healthcare providers' knowledge, attitudes, and practices toward integrating evidence-based practice and artificial intelligence in Saudi Arabia: a cross-sectional study. [PDF]

BMC Health Serv Res
Alhazmi A, Mohieldin A, Muzammil K, Ali H, Khan MS, Ali M, Hawash MM, Alqahtani RM, Dawria A.   +8 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Types of Evidence Synthesis Beyond Systematic Reviews in Evidence-Based Practice Publications in Audiology Research: A Tutorial. [PDF]

J Am Acad Audiol
Gaeta L, Stark RK.
europepmc   +1 more source

Evidence based Practice at WUWHS

International Wound Journal, 2008
openaire   +3 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Evidence-based practice among physiotherapists in India: a nationwide survey of knowledge, attitude, and implementation behavior. [PDF]

PeerJ
Sidiq M, Sharma J, Janakiraman B, Kashoo F, Chahal A, Varshney R, Ansari S, Pandey A, Rai RH, Khormi A, Khan I, Alshehri MM, Aldhahi MI.   +12 more
europepmc   +1 more source