Results 51 to 60 of about 5,781,005 (277)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Resistance decay in individuals after antibiotic exposure in primary care: a systematic review and meta-analysis

BMC Medicine, 2018
Background Antibiotic resistance is an urgent global problem, but reversibility is poorly understood. We examined the development and decay of bacterial resistance in community patients after antibiotic use.
Mina Bakhit, Tammy Hoffmann, Anna Mae Scott, Elaine Beller, John Rathbone, Chris Del Mar   +5 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Study protocol for a pragmatic randomised multiple baseline trial evaluating Knowledge Insight Tools (KIT), a cognitive behavioural therapy-informed school-based counselling intervention for children and young people in UK secondary schools with low mood and anxiety

Trials
Background There is a pressing need to offer more accessible, evidence-based psychological interventions to secondary school students who are increasingly reporting difficulties with anxiety and low mood.
Matthew Paul Constantinou, Jessica Stepanous, Suzet Tanya Lereya, Hannah Wilkinson, Sarah Golden, Jessica Deighton   +5 more
doaj   +1 more source

Perceptions of Nursing Students Regarding Evidence-Based Practice [PDF]

, 2009
The purpose of this descriptive quantitative study was to explore the nursing students\u27 perceptions of their attitude and knowledge regarding evidence-based practice (EBP).
Tolentino, Sheleen
core   +1 more source

Implementing change in primary care practice: lessons from a mixed-methods evaluation of a frailty initiative [PDF]

, 2018
© 2018, BJGP Open. Background: The NHS is facing increasing needs from an aging population, which is acutely visible in the emerging problem of frailty. There is growing evidence describing new models of care for people living with frailty, but a lack of
Bryce, Carol, Fleming, Joanna, Reeve, Joanne   +2 more
core   +1 more source

Applying evidence-based medicine in general practice : a video-stimulated interview study on workplace-based observation [PDF]

, 2020
BACKGROUND: Evidence-based medicine (EBM) in general practice involves applying a complex combination of best-available evidence, the patient's preferences and the general practitioner's (GP) clinical expertise in decision-making.
Bartelink, Marie-Louise EL, Damoiseaux, Roger AMJ, de Groot, Esther, Pype, Peter, Suijker, Hilde A, Van Roy, Kaatje, Welink, Lisanne S   +6 more
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Effects of task-shifting from primary care physicians to nurses: an overview of systematic reviews

Human Resources for Health
Background Task-shifting from primary care physicians (PCPs) to nurses is a means of overcoming PCP shortages and meeting the needs of patients receiving primary care.
Muna Paier-Abuzahra, Nicole Posch, Klaus Jeitler, Thomas Semlitsch, Christina Radl-Karimi, Ulrike Spary-Kainz, Karl Horvath, Andrea Siebenhofer   +7 more
doaj   +1 more source

Friendly visiting by a volunteer for reducing loneliness or social isolation in older adults: A systematic review

Campbell Systematic Reviews, 2023
Background Loneliness and social isolation are currently among the most challenging social issues. Given their detrimental impact on physical and mental health, identifying feasible and sustainable interventions to alleviate them is highly important ...
Jorien Laermans, Hans Scheers, Philippe Vandekerckhove, Emmy De Buck   +3 more
doaj   +1 more source