Results 121 to 130 of about 6,984,241 (359)

Senate Bill 91: Summary of Policy Reforms [PDF]

open access: yes, 2016
Complete issue of Alaska Justice Forum 33(1), Spring 2016 at https://scholarworks.alaska.edu/handle/11122/6883.This article highlights provisions of Senate Bill 91, "Omnibus Criminal Law & Procedure; Corrections Act," related to the recommendations of ...
UAA Justice Center
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Report: Fostering a Movement Towards Evidence-Based Screening, Assessment, and Treatment [PDF]

open access: yes, 2010
https://digitalscholar.lsuhsc.edu/soph_wp/1027/thumbnail ...
and Justice, Institute for Public Health   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Mapping research on evidence-based practice in education: a mixed analysis

open access: yesRED. Revista de Educación a Distancia
This work is a review approach to the scientific literature on evidence-based practice in teaching/learning processes carried out through a bibliometric study and a content analysis.
Mayara Lustosa de Oliveira Barbosa   +3 more
doaj   +1 more source

Brief: Fostering a Movement Towards Evidence-Based Screening, Assessment, and Treatment [PDF]

open access: yes, 2011
https://digitalscholar.lsuhsc.edu/soph_wp/1026/thumbnail ...
and Justice, Institute for Public Health   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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