Results 171 to 180 of about 6,984,241 (359)

Handbook of Evidence-Based Practices in Intellectual and Developmental Disabilities

, 2016
Nirbhay N. Singh
semanticscholar   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Barriers to integrating evidence-based practices into intrapartum care during vaginal births: a descriptive qualitative study in Sri Lanka. [PDF]

BMJ Open
Weerasingha TK, Ratnayake C, Rathnayake A, Tennakoon SUB.   +3 more
europepmc   +1 more source

Training Teachers to use Evidence-Based Practices for Autism: Examining Procedural Implementation fidelity.

Psychology in the schools (Print), 2015
Aubyn C. Stahmer, Sarah R. Reed, Ember Lee, Erica M. Reisinger, J. Connell, D. Mandell   +5 more
semanticscholar   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Expansion of Personas to Guide Professional Development in Implementing Evidence-Based Practices in Diverse Institutions. [PDF]

CBE Life Sci Educ
Dunbar-Wallis AK, Zagallo P, Meeder A, Schwartz Z, Groenevelt E, Bilinski T, Jaeger D, Corwin L.   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Implementing Evidence-Based Practices in Hospitals: A Narrative Review of Implementer Roles and Project Attributes. [PDF]

Nurs Res Pract
Arsenault Knudsen ÉN, Krainak K, Ruona M.   +2 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Challenges Implementing Youth-Focused Evidence-Based Practices in Rural Areas: A Rapid Ethnographic Study. [PDF]

Rural Ment Health
Triplett NS, Nahabedian S, Mirzoyev H, Liu L, AlRasheed R.   +4 more
europepmc   +1 more source