Results 191 to 200 of about 805,739 (261)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Enhancing perinatal care in Rwanda: building quality improvement into system strengthening. [PDF]

open access: yesBMJ Paediatr Open
Tuyisenge L   +10 more
europepmc   +1 more source

Clinical audit and quality improvement: rivals, partners, or one and the same? [PDF]

open access: yesFront Health Serv
Davey N   +4 more
europepmc   +1 more source

Quality Improvement Competencies for Health Care Quality Professionals: Protocol for a Scoping Review. [PDF]

open access: yesJMIR Res Protoc
Shaharuddin N   +7 more
europepmc   +1 more source

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