Results 191 to 200 of about 861,456 (261)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Exercise Prescription for Falls Prevention in Older Adults: A Before-After Study of an Online Educational Course for Fitness Instructors. [PDF]

J Aging Res
Hennell JM, Pogrebnoy D, Gorelik A, Haas R.   +3 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Implementation of evidence-based practice guidelines to prevent urinary retention in hospitals: A process evaluation in orthopaedic care. [PDF]

PLoS One
Hälleberg-Nyman M, Fjordkvist E, Joelsson-Alm E, Winberg M, Hommel A, Ostaszkiewicz J, Wallin L, Eldh AC.   +7 more
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Sustained Reduction of Ventilator-Associated Pneumonia Through a Structured Interdisciplinary Quality Improvement Strategy. [PDF]

Cureus
Austin CL, Day L, Draper B.
europepmc   +1 more source

Neonatal Hypothermia in Mogadishu, Somalia: Strengthening Thermal Care Beyond NICU Equipment. [PDF]

Res Rep Trop Med
Hassan HA, Hassan WM.
europepmc   +1 more source

Translating laboratory quality management system into practice: strategic opportunities and challenges for ISO 15189:2022 implementation in Nigeria's healthcare system. [PDF]

Front Health Serv
Basil B, Okoro NI, Mba IN, Myke-Mbata BK.   +3 more
europepmc   +1 more source