Results 101 to 110 of about 12,163,693 (291)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Rapid Evidence Review: Covid-19 contact tracing [PDF]

open access: yes, 2020
n most scenarios, highly effective contact tracing and case isolation is enough to control a new outbreak of COVID-19 within 3 months.For contact tracing to be an effective public health measure requiressecondary cases to be discovered before they become
National Health Library and Knowledge Service Evidence Team
core  

Un nuovo immaginario: l’amministrazione dell’evidenza

open access: yesIm@go. A Journal of the Social Imaginary, 2015
This article introduces the journal section devoted to “The imagery of evaluation”, focusing on evaluation as a major technology of government in the “Evaluative State”, on the ideas of objectivity, transparency and evidence produced by the algorithmic ...
Valeria Pinto
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Summary Document: COVID-19 Incubation Period

open access: yes, 2020
National Health Library and Knowledge Service | Evidence TeamSummary Document: COVID-19Incubation Period1The following information resources have been selected by the National Health Library and Knowledge Service Evidence Virtual Team in response to a ...
National Health Library and Knowledge Service Evidence Team
core  

What is the evidence for harm minimisation measures in gambling venues? [PDF]

open access: yes, 2014
What techniques are currently being used for electronic gambling machine harm minimisation, and do they work? Overview The use of electronic gambling machines (EGMs) in Australia and New Zealand constitutes the largest sector of the gambling industry ...
Louise Francis   +2 more
core  

Rapid evidence profile #33: What is known from the evidence about optimizing out-of-hospital surgical capacity to reduce waitlists?

open access: yes, 2022
An overview of the best available research evidence from around the world (i.e., evidence syntheses) and local research evidence (i.e., single studies) and may include a scan of experiences from other countries and from Canadian provinces and territories,
Alam, S   +8 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Infinite Time and the Boltzmann Brain Hypothesis

open access: yesPhilosophies
Many argue that the standard understanding of the second law of thermodynamics combined with the supposition, backed by recent scientific evidence, that the future is infinite entails that one is, most likely, a momentary Boltzmann brain that will ...
M. Joshua Mozersky
doaj   +1 more source

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