Results 91 to 100 of about 4,902,909 (340)

Awareness, attitudes and knowledge about evidence based medicine among doctors in Gaza:A cross sectional survey [PDF]

open access: yes, 2017
Evidence-based medicine (EBM) has emerged as a strategy to integrate research evidence within clinical decision-making. We have explored awareness, knowledge and attitudes about EBM among doctors in the Gaza Strip. In 2014, we conducted a cross-sectional
Albarqouni, Loai, Elessi, Khamis
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Does therapeutic massage support mental well-being? [PDF]

open access: yes, 2012
Massage was once a traditional medical practice of many ancient cultures. Today, the practice of modern therapeutic massage is embedded within the field of complementary or alternative medicine (CAM).
Cavaye, Joyce
core   +1 more source

Curso de aperfeiçoamento em saúde baseada em evidências por teleconferência [PDF]

open access: yes, 2009
Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Division of Emergency Medicine and Evidence-Based MedicineBrazilian Cochrane CenterAssociação Paulista de ...
Atallah, Álvaro Nagib   +1 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Reconstructing data : evidence-Based Medicine and Evidence-Based Public Health in context [PDF]

open access: yes, 2006
The emergence of Evidence-Based Medicine (EBM) as the gold-standard practice in biomedicine and public health practices represents a significant epistemological turn in modern medicine.
Davidovitch, Nadav, Filc, Dani
core   +5 more sources

Natalizumab in patients with multiple sclerosis in Colombia: a case series

open access: yesActa Neurológica Colombiana, 2020
INTRODUCTION: Natalizumab is a humanized monoclonal antibody prescribed in the treatment of multiple sclerosis, the most prevalent chronic and inflammatory disease of the central nervous system (CNS). NEDA (no evidence of disease activity) status is the
Juan Raúl García Bonitto   +4 more
doaj   +1 more source

Bad news: analysis of the quality of information on influenza prevention returned by Google in English and Italian [PDF]

open access: yes, 2015
Information available to the public influences the approach of the population toward vaccination against influenza compared with other preventative approaches.
Allam   +38 more
core   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Developments, Evolution, and Implications of National Diagnostic Criteria for COVID-19 in China

open access: yesFrontiers in Medicine, 2020
Recently WHO has characterized COVID-19 as a pandemic. Diagnosing the disease accurately and decreasing misdiagnoses and missed diagnoses is very important for management.
Lin-Lu Ma   +6 more
doaj   +1 more source

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