Results 201 to 210 of about 2,826,441 (245)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Investigating the knowledge attitude and practice of evidence based medicine education in Sudanese medical students: a cross sectional study. [PDF]

BMC Med Educ
Amin MHJ, Awad MH, Mohamed Ginawi ES, Mohammed ASK, Noureldaiem Ibrahim EHE, Yassen OYM, Elomeiri LESMA, Hakim Hussain AHMA, Eltahir TA, Mohmmed FSAA, Wedatalla RAE, Awad KH, Mahgoub RKE, Karar AMA, Saeed AYM, Mohamed AEA, Mohamed Ginawi RS, Sidar FMK, Saifalsorori RRA, Osman OIA, Nouri MAI, Mohamed MAA, Ibrahim NBM, Mohamed MMM, Mohamed AEAB, MohamedAhmed FMA, Hassan MRM, Mohamed SAA, Bashar Hadi HE, Gandour HMNG, Ahmed NAF, Ahmed NME, Osman MMAA, Elhadi SEI.   +33 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Evidence-Based Medicine: <i>Knowledge, attitudes and practices among senior medical students and interns in Oman</i>. [PDF]

Sultan Qaboos Univ Med J
Al-Hadhrami RS, Al-Shaqsi AN, Thuhli ZMA, Sabbari MYA.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Analysis of factors associated with substandard nutrition in critically ill patients and the effect of applying enteral nutrition nursing model based on evidence-based medicine: A retrospective observational study. [PDF]

Medicine (Baltimore)
Wang J, Wang J, Ye X, Lu Q, Liu Y.
europepmc   +1 more source

Assessment of knowledge, attitudes, practices, and self-efficacy toward evidence-based medicine among resident physicians: a cross-sectional study from Qatar. [PDF]

Front Med (Lausanne)
Mohammed Ahmed W, Aabdien M, Mohamed A, Bougmiza MI.   +3 more
europepmc   +1 more source

GLP-1 receptor agonist for weight loss and fertility: Social media and online perception versus evidence-based medicine. [PDF]

PLoS One
Merhi Z, Karekar M, Mouanness M.
europepmc   +1 more source

The impact of evidence-based medicine curricula on information literacy among clinical medical undergraduates and postgraduates in China. [PDF]

BMC Med Educ
Wang C, Yao Y, Chen Y, Chen J.
europepmc   +1 more source

"I still have not mastered that skill!" Medical student perspectives on a simulation-based evidence-based medicine competency assessment. [PDF]

J Med Libr Assoc
Nicholson J, Plovnick C, Magro J, van der Vleuten C, de Bruin A, Kalet A.   +5 more
europepmc   +1 more source