Results 51 to 60 of about 4,902,909 (340)
Integrative Medicine Research, 2022 Background: Myasthenia Gravis (MG) is a disorder of neuromuscular transmission bringing mild ocular weakness to severe generalized muscle weakness and disability. The conventional treatments have long-term side effects, and Chinese herbal medicines (CHM)
Si-jia Zhu +8 more
doaj +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Chinese Medicine, 2017 Background Both cupping therapy and acupuncture have been used in China for a long time, and their target indications are pain-related conditions. There is no systematic review comparing the effectiveness of these two therapies. Objectives To compare the
Ya-Jing Zhang +6 more
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BMC Complementary Medicine and Therapies, 2020 Background Ulcerative colitis, characterized by diarrhea, bloody stools and abdominal pain, is a chronic, idiopathic inflammatory disease of the colonic mucosa.
Xiao Wang +6 more
doaj +1 more source
The compass, crow's nest and ship of medicine in the sea of uncertainties [PDF]
, 2009 Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Discipline of Emergency Medicine and Evidence-Based MedicineAssociação Paulista de MedicinaUNIFESP, EPM, Discipline of Emergency Medicine and Evidence-Based ...
Atallah, Álvaro Nagib
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Quality healthcare, evidence-based medicine and translational research [PDF]
, 2011 Advances in medical care ensure that with the passage of time we are increasingly able to effectively tackle diverse medical problems. These advances, however, do come at a cost and the benefits derived need to be assessed on a regular basis.
Vassallo, Josanne
core
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
BMC Medical Research MethodologyIntroduction Interrupted time series (ITS) design is a commonly used method for evaluating large-scale interventions in clinical practice or public health. However, improperly using this method can lead to biased results.
Yuanjin Zhang +9 more
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Contexts of diffusion: Adoption of research synthesis in Social Work and Women's Studies
, 2014 Texts reveal the subjects of interest in research fields, and the values, beliefs, and practices of researchers. In this study, texts are examined through bibliometric mapping and topic modeling to provide a birds eye view of the social dynamics ...
A. Abbott +14 more
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