Results 81 to 90 of about 5,564,521 (297)

Usability Study Identifies Vocabulary, Facets, and Education as Primary Primo Discovery System Interface Problems

open access: yesEvidence Based Library and Information Practice, 2017
A Review of: Brett, K. R., Lierman, A., & Turner, C. (2016). Lessons learned: A Primo usability study. Information Technology and Libraries, 35(1), 7-25.
Ruby Muriel Lavallee Warren
doaj   +1 more source

CDFIs Stepping into the Breach: An Impact Evaluation—Summary Report [PDF]

open access: yes, 2015
This report summarizes research undertaken by the Carsey School of Public Policy to evaluate impacts of the Community Development Financial Institutions (CDFI) Fund on CDFIs and of the CDFI industry on the people and communities it serves. In summary, we
Hangen, Eric   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Management and drivers of change of pollinating insects and pollination services. National Pollinator Strategy: for bees and other pollinators in England, Evidence statements and Summary of Evidence [PDF]

open access: yes
These Evidence Statements provide up-to-date information on what is known (and not known) about the status, values, drivers of change, and responses to management of UK insect pollinators (as was September 2018). This document has been produced to inform
Baldock, K.C.R   +10 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

On the use of Fixed Trip Matrices for the Evaluation of Urban Highway Schemes [PDF]

open access: yes, 1985
This paper begins with a summary of the theoretical background to the question of fixed or variable trip matrices and briefly reviews current UK advice and practice.
Bonsall, P.W.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Model Correlates Many Factors to Undergraduates’ Perceived Importance of Library and Research Activities, but Low Explanation Power Suggests More Research Needed

open access: yesEvidence Based Library and Information Practice, 2014
A Review of: Soria, K. M. (2013). Factors predicting the importance of libraries and research activities for undergraduates. Journal of Academic Librarianship, 39(6), 464-470.
Diana K. Wakimoto
doaj   +1 more source

Silver Dreams Fund Learning and Evaluation Contract: Final report June 2014 [PDF]

open access: yes, 2014
This is a summary of the Final Report which presents the findings of the evaluation of the Big Lottery Fund's Silver Dreams Fund conducted by Ecorys.The Silver Dreams Fund was a £10 million programme which sought to address the gaps in provision by ...
Louise Scott   +4 more
core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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