Results 61 to 70 of about 5,054,449 (279)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Surprising gifts: Theory and laboratory evidence [PDF]
Journal of Economic Theory, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kiryl Khalmetski +2 more
openaire +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Modeling of random static loads on a structural cover with limited statistical data
Structural Mechanics of Engineering Constructions and Buildings, 2020 Relevance. Loads on structures are complex stochastic elements that include several types of uncertainties simultaneously. The article describes a probabilistic approach to the load modeling on structural covers taking into account limited statistical ...
Sergey A. Solovev
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Evidence Theory and VPRS model
Electronic Notes in Theoretical Computer Science, 2003 AbstractThe Rough Set Theory (RST) was proposed by Pawlak [4] as a new mathematical approach to deal with uncertain knowledge in expert systems. In 1991 Ziarko [11] proposed the Variable Precision Rough Set Model (VPRSM) as a certain extension of the rough set theory.
Marszał-Paszek, Barbara, Paszek, Piotr
openaire +3 more sources
Evidence-based Policy: Where Is Our Theory of Evidence? [PDF]
Journal of Children's Services, 2008 This article critically analyses the concept of evidence in evidence‐based policy, arguing that there is a key problem: there is no existing practicable theory of evidence, one which is philosophically‐grounded and yet applicable for evidence‐based policy. The article critically considers both philosophical accounts of evidence and practical treatments
Cartwright, N. +2 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Imitation - Theory and Experimental Evidence [PDF]
We introduce a generalized theoretical approach to study imitation models and subject the models to rigorous experimental testing. In our theoretical analysis we find that the different predictions of previous imitation models are due to different ...
Jose Apesteguia +2 more
core +3 more sources
Finance and Inequality: Theory and Evidence [PDF]
Annual Review of Financial Economics, 2009 In this paper, we critically review the literature on finance and inequality, highlighting substantive gaps in the literature. Finance plays a crucial role in the preponderance of theories of persistent inequality. Unsurprisingly, therefore, economic theory provides a rich set of predictions concerning both the impact of finance on inequality and about
Demirguc-Kunt, Asli, Levine, Ross
openaire +4 more sources