Results 161 to 170 of about 7,245,481 (315)

The absence of evidence is not the evidence of absence [PDF]

Human Reproduction, 2015
Silvia, Sánchez-Ramón, Alejandra, Comins-Boo, María, Núñez Beltrán, Áurea, García Segovia, Juana, Gil Herrera   +4 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

IL-33-induced neuroimmune regulation in depression: A narrative review from molecular mechanisms to therapeutic potential. [PDF]

Medicine (Baltimore)
Wang G, Zhang X, Duan G, Yuan S.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Factors affecting survival in patients with colorectal cancer: an umbrella review. [PDF]

J Transl Med
Yu L, Yuan J, Lou S, Huang A, Cai X, Ji J, Dai X, Mao X, Mao Y, Sun L.   +9 more
europepmc   +1 more source

The evidence for evidence-based medicine

Complementary Therapies in Medicine, 2000
R, Imrie, D W, Ramey
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Serum lipid profile patterns in patients with oral cancer and oral potentially malignant disorders. [PDF]

Bioinformation
Singh P, Gupta S, Gupta G, Patidar D, Patidar D, Gupta I.   +5 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Retraction: How to promote the balanced development of urban and rural China? Evidences from reallocating idle rural residential land of Zhejiang province, China. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source