Results 171 to 180 of about 7,245,481 (315)

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

16S rRNA analysis of proximal dental plaque bacteria reveals that daily use of commercialized disposable dental floss Itoyoji^® in addition to appropriate tooth brushing slightly gives influence on the bacterial composition. [PDF]

BMC Oral Health
Yamanaka T, Kaji K, Onishi A, Terashima M, Maesoma A, Tani A, Ogata Y, Toyama T, Ishikawa Y, Kuramitsu S, Hayashi T, Shuto T, Kakimoto K.   +12 more
europepmc   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Evidences of topological nodal line semimetal in Mn₃GaC: Anomalous Hall effect, thermal transport and DFT studies. [PDF]

Sci Rep
Gangwar S, Choudhury A, Maitra T, Yadav CS.   +3 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Comments regarding "Current evidence gaps to support systematic cytomegalovirus screening in pregnancy". [PDF]

EClinicalMedicine
Périllaud-Dubois C, Picone O, Vivanti AJ, Ville Y, Vauloup-Fellous C.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Myeloid-Derived Suppressor Cells and Radiotherapy: Regulation and Clinical Implications. [PDF]

J Cancer
Yang L, Wang K, Zeng W, Lu Y, Sheng H, Xiong H, Zhang H.   +6 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Long-term management of aortic stenosis (surgery and transcatheter options in young patients): a case report of valve-in-valve transcatheter aortic valve implantation. [PDF]

Eur Heart J Case Rep
Russo G, Marchetta M, Moschovitis A, Sangiorgi GM, Taramasso M.   +4 more
europepmc   +1 more source