Results 41 to 50 of about 30,895 (213)

Extracellular Vesicles-Mimetic Encapsulation Improves Oncolytic Viro-Immunotherapy in Tumors With Low Coxsackie and Adenovirus Receptor

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
The oncolytic adenovirus (Adv) exhibited poor infection efficiency in tumor cells with low coxsackie and adenovirus receptor (CAR) on the cell surface, which limits the therapeutic efficacy of the Adv-mediated cancer gene therapy.
Yonghui Zhang   +7 more
doaj   +1 more source

Formally Verified EVM Block-Optimizations

open access: yes, 2023
AbstractThe efficiency and the security of smart contracts are their two fundamental properties, but might come at odds: the use of optimizers to enhance efficiency may introduce bugs and compromise security. Our focus is on (Ethereum Virtual Machine) block-optimizations, which enhance the efficiency of jump-free blocks of opcodes by eliminating ...
Elvira Albert   +3 more
openaire   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet   +17 more
wiley   +1 more source

EVM Prediction for Massive MIMO [PDF]

open access: yes2019 IEEE 30th Annual International Symposium on Personal, Indoor and Mobile Radio Communications (PIMRC), 2019
Signal to interference plus noise ratio (SINR) is a widely common performance metric used in the majority of massive multiple-input, multiple-output (Ma-MIMO) research. This metric requires prior knowledge of the user channel vectors and the interference caused by inaccurate channel state information (CSI).
Boukley Hasan, Wael A G   +3 more
openaire   +3 more sources

VolumeEVM: A new surface/volume integrated model [PDF]

open access: yes, 2003
Volume visualization is a very active research area in the field of scien-tific visualization. The Extreme Vertices Model (EVM) has proven to be a complete intermediate model to visualize and manipulate volume data using a surface rendering approach ...
Ayala Vallespí, M. Dolors   +1 more
core   +1 more source

On the error vector magnitude as a performance metric and comparative analysis

open access: yes, 2006
In this paper, we present the error vector magnitude (EVM) as a a figure of merit for assessing the quality of digitally modulated telecommunication signals.
Ashraf, Nabil Shovon   +3 more
core   +1 more source

A‐optimal model‐based design of experiments for processes with uncertain inputs

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Model‐based design of experiments (MBDoE) techniques are tools for selecting experimental conditions that enable accurate parameter estimation for mechanistic models. Most MBDoE approaches assume that the selected experimental conditions will be implemented perfectly, without uncertainties in the independent variables.
Bright Ofori   +3 more
wiley   +1 more source

A Geometrical Characterization of the Twin Paradox and its Variants [PDF]

open access: yes, 2010
The aim of this paper is to provide a logic-based conceptual analysis of the twin paradox (TwP) theorem within a first-order logic framework. A geometrical characterization of TwP and its variants is given.
A. Einstein   +22 more
core   +1 more source

Study on the composite fracture characteristics of filling and reinforcing cracked rock mass after high temperature damage

open access: yesDeep Underground Science and Engineering, EarlyView.
Cement infill shares compressive and shear stresses during loading, while interfacial friction hinders crack propagation and reduces stress concentration, improving the rock's load‐bearing capacity. Failure modes vary with crack inclination. Unfilled specimens show four modes.
Shihao Yuan   +4 more
wiley   +1 more source

UMTS radio-over-fiber pico-cell interconnection employing uncooled DFB lasers for multi-mode fibre modulation bandwidth enhancement [PDF]

open access: yes, 2009
This paper analyzes experimentally the use of distributed feedback lasers (DFB) in order to increase modulation bandwidth in multimode fibres, enabling 3 km bidirectional radio-over-multimode fibre UMTS transmission in a frequency-division duplexing (FDD)
Alemany, Ruben   +2 more
core   +1 more source

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