Results 141 to 150 of about 53,740 (260)

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Myoclonus

Movement Disorders Clinical Practice, EarlyView.
Masashi Hamada
wiley   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

Cell Proliferation, EarlyView.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng, Zuping Wu, Mengjie Wu, Liang Xie, Qianming Chen   +4 more
wiley   +1 more source

Tremor as an intrinsic feature of juvenile myoclonic epilepsy

Epilepsia, Volume 66, Issue 3, Page e47-e53, March 2025.
Abstract We aim to understand whether tremor may be an intrinsic feature of juvenile myoclonic epilepsy (JME) and whether individuals with JME plus tremor experience a different disease course. Thirty‐one individuals with JME plus tremor (17 females, mean age = 33.9 ± 13.8 years) and 30 age of onset‐ and gender‐matched subjects with JME (21 females ...
Alessia Giugno, Francesco Fortunato, Ilaria Sammarra, Miriam Sturniolo, Enrico Fratto, Iolanda Martino, Rita Nisticò, Antonio Gambardella   +7 more
wiley   +1 more source

Tumor‐related epilepsy in glioma: A multidisciplinary overview

Epilepsia, EarlyView.
Abstract Seizures are a common and challenging symptom in brain tumors, affecting approximately 60% of patients. Tumor‐related epilepsy (TRE) in glioma patients requires personalized and dynamic management in a multidisciplinary environment, especially for its intricate pathophysiology and unpredictable disease evolution. This investigation provides an
Roberto Michelucci, Giada Pauletto, Antonio Silvani, Elena Pasini, Tamara Ius, Matteo Martinoni, Carlo Alberto Castioni, Andrea Salmaggi, Sofia Asioli, Marta Maschio, Giuseppe Minniti, Enrico Franceschi, Flavio Villani, Roberta Rudà, Eleonora Aronica, the Italian Multidisciplinary Group for Tumor Epilepsy, Paolo Vitali, Damiano Balestrini, Elisa D’Angelo, Lorenzo Bello, Marco Rossi, Marta Padovan, Anna Teresa Giallonardo, Carlo di Bonaventura, Francesco Toni, Angela La Neve, Simona Rizzato, Matteo Pugnaghi, Marco Vindigni, Carmelo Sturiale   +29 more
wiley   +1 more source

Familial adult myoclonus epilepsy: A comprehensive diagnostic strategy for clinical practice

Epilepsia, EarlyView.
Abstract Familial adult myoclonus epilepsy (FAME) is a genetic neurological disorder characterized by cortical myoclonus and epileptic seizures with clinical features that overlap with other movement disorders and epileptic syndromes, particularly essential tremor (ET), progressive myoclonic epilepsy (PME), and juvenile myoclonic epilepsy (JME).
Yitao Lu, Yi Ge, Ruyi Wang, Yang Zheng, Jiping Zhou, Zhongjin Wang, Chunhong Shen, Shan Wang, Lingli Hu, Bo Wang, Zhidong Cen, Wei Luo, Meiping Ding, Shuang Wang, Yao Ding   +14 more
wiley   +1 more source

Drug discovery and preclinical testing of drug candidates for developmental and epileptic encephalopathies

Epilepsia, EarlyView.
Abstract Drug development for developmental and epileptic encephalopathies (DEEs) follows different strategies on one hand including disease‐targeting precision medicine approaches considering the genetic variants and pathomechanisms in DEEs and on the other hand including therapeutic approaches with novel targets or second‐generation drug candidates ...
Heidrun Potschka, Daniel Pérez‐Pérez
wiley   +1 more source

Are patients with Parkinson's disease impaired in the recognition of emotion's authenticity?

Journal of Neuropsychology, EarlyView.
Abstract In recognising emotions expressed by others, one can make use of both embodied cognition and mechanisms that do not necessarily require activation of the limbic system, such as evoking from memory the meaning of morphological features of the observed face.
Agnese Anzani, Stefano Zago, Teresa Difonzo, Cristina Scarpazza, Nadia Bolognini, Giulia Franco, Alessio Difonzo, Maria Cristina Saetti   +7 more
wiley   +1 more source

Effects of repetitive mechanical tactile stimulation interventions with stationary and moving patterns on paired-pulse depression. [PDF]

BMC Neurosci
Watanabe H, Kojima S, Otsuru N, Onishi H.   +3 more
europepmc   +1 more source