Results 141 to 150 of about 180,175 (329)

Drug discovery and preclinical testing of drug candidates for developmental and epileptic encephalopathies

open access: yesEpilepsia, EarlyView.
Abstract Drug development for developmental and epileptic encephalopathies (DEEs) follows different strategies on one hand including disease‐targeting precision medicine approaches considering the genetic variants and pathomechanisms in DEEs and on the other hand including therapeutic approaches with novel targets or second‐generation drug candidates ...
Heidrun Potschka, Daniel Pérez‐Pérez
wiley   +1 more source

Epilepsy in dentatorubral–pallidoluysian atrophy: A systematic review and meta‐analysis

open access: yesEpilepsia, EarlyView.
Summary of key clinical and electrophysiological characteristics of DRPLA‐related epilepsy from a systematic review and meta‐analysis of 1,191 patients. DRPLA patients with epilepsy showed earlier disease onset, longer CAG repeat expansion, and a tendency toward paternal inheritance. EEG findings frequently included photoparoxysmal responses.
Toru Horinouchi   +10 more
wiley   +1 more source

Treatment approaches in posthypoxic myoclonus: A narrative review with expert opinion

open access: yesEpilepsia, EarlyView.
Abstract Acute posthypoxic myoclonus (PHM) is a neurological complication that typically emerges within 12–48 h following cardiac arrest, often in comatose patients. It can present as generalized, multifocal, or focal myoclonus and has traditionally been associated with poor prognosis.
Marina Romozzi   +7 more
wiley   +1 more source

Cone beam computed tomographic myelography in horses with cervical vertebral compressive myelopathy

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background While computed tomographic (CT) myelography is increasingly available and has been evaluated in alive horses, objective criteria for diagnosing cervical vertebral compressive myelopathy (CVCM) are lacking. Objectives To establish morphometric dimensions of the cervical vertebral canal and spinal cords from horses with CVCM and ...
Sonia González‐Medina   +4 more
wiley   +1 more source

Persistent postural‐perceptual dizziness versus vestibular migraine: A narrative review

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This article reviews the differences and similarities between persistent postural‐perceptual dizziness (PPPD) and vestibular migraine. Background PPPD is considered a chronic functional vestibular disorder characterized by persistent dizziness, unsteadiness, nonspinning vertigo, and often exacerbated by upright posture, movement, or ...
David Moreno‐Ajona
wiley   +1 more source

Intraoperative changes in transcranial motor evoked potentials and somatosensory evoked potentials predicting outcome in children with intramedullary spinal cord tumors.

open access: yesJournal of Neurosurgery: Pediatrics, 2014
Jason S. Cheng   +5 more
semanticscholar   +1 more source

Evoked potentials in immobilized cats to a combination of clicks with painful electrocutaneous stimuli [PDF]

open access: yes
Averaged evoked potentials in the auditory, somatosensory, and motor cortical zones, as well as in the mesencephalic reticular formation were recorded in acute experiments on nonanesthetized, immobilized cats.
Gilinskiy, M. A., Korsakov, I. A.
core   +1 more source

Amplifying and ameliorating light avoidance in mice with photoreceptor targeting and calcitonin gene‐related peptide sensitization

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The aim of this study was to determine the photoreceptor basis of light avoidance in mice and assess the effect of CGRP sensitization on this behavior. Background Prior studies have suggested that photophobia is mediated by a subset of retinal ganglion cells (RGCs) that contain melanopsin, making them intrinsically photosensitive ...
Eric A. Kaiser   +3 more
wiley   +1 more source

Evidence-based guideline update: Intraoperative spinal monitoring with somatosensory and transcranial electrical motor evoked potentials

open access: yesNeurology, 2012
M. Nuwer   +11 more
semanticscholar   +1 more source

Differences in response inhibition between medication‐free patients with obsessive‐compulsive disorder with and without sensory phenomena

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Obsessive‐compulsive disorder (OCD) is a heterogeneous disorder, and approximately 70% of patients with OCD experience sensory phenomena (SP). Previous studies have revealed that patients with OCD exhibit a deficit in response inhibition (RI). However, few studies have investigated the relationship between SP and RI in patients with OCD.
Keitaro Murayama   +7 more
wiley   +1 more source

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