Results 141 to 150 of about 180,175 (329)
Abstract Drug development for developmental and epileptic encephalopathies (DEEs) follows different strategies on one hand including disease‐targeting precision medicine approaches considering the genetic variants and pathomechanisms in DEEs and on the other hand including therapeutic approaches with novel targets or second‐generation drug candidates ...
Heidrun Potschka, Daniel Pérez‐Pérez
wiley +1 more source
Epilepsy in dentatorubral–pallidoluysian atrophy: A systematic review and meta‐analysis
Summary of key clinical and electrophysiological characteristics of DRPLA‐related epilepsy from a systematic review and meta‐analysis of 1,191 patients. DRPLA patients with epilepsy showed earlier disease onset, longer CAG repeat expansion, and a tendency toward paternal inheritance. EEG findings frequently included photoparoxysmal responses.
Toru Horinouchi +10 more
wiley +1 more source
Treatment approaches in posthypoxic myoclonus: A narrative review with expert opinion
Abstract Acute posthypoxic myoclonus (PHM) is a neurological complication that typically emerges within 12–48 h following cardiac arrest, often in comatose patients. It can present as generalized, multifocal, or focal myoclonus and has traditionally been associated with poor prognosis.
Marina Romozzi +7 more
wiley +1 more source
Cone beam computed tomographic myelography in horses with cervical vertebral compressive myelopathy
Abstract Background While computed tomographic (CT) myelography is increasingly available and has been evaluated in alive horses, objective criteria for diagnosing cervical vertebral compressive myelopathy (CVCM) are lacking. Objectives To establish morphometric dimensions of the cervical vertebral canal and spinal cords from horses with CVCM and ...
Sonia González‐Medina +4 more
wiley +1 more source
Persistent postural‐perceptual dizziness versus vestibular migraine: A narrative review
Abstract Objective This article reviews the differences and similarities between persistent postural‐perceptual dizziness (PPPD) and vestibular migraine. Background PPPD is considered a chronic functional vestibular disorder characterized by persistent dizziness, unsteadiness, nonspinning vertigo, and often exacerbated by upright posture, movement, or ...
David Moreno‐Ajona
wiley +1 more source
Evoked potentials in immobilized cats to a combination of clicks with painful electrocutaneous stimuli [PDF]
Averaged evoked potentials in the auditory, somatosensory, and motor cortical zones, as well as in the mesencephalic reticular formation were recorded in acute experiments on nonanesthetized, immobilized cats.
Gilinskiy, M. A., Korsakov, I. A.
core +1 more source
Abstract Objective The aim of this study was to determine the photoreceptor basis of light avoidance in mice and assess the effect of CGRP sensitization on this behavior. Background Prior studies have suggested that photophobia is mediated by a subset of retinal ganglion cells (RGCs) that contain melanopsin, making them intrinsically photosensitive ...
Eric A. Kaiser +3 more
wiley +1 more source
Abstract Obsessive‐compulsive disorder (OCD) is a heterogeneous disorder, and approximately 70% of patients with OCD experience sensory phenomena (SP). Previous studies have revealed that patients with OCD exhibit a deficit in response inhibition (RI). However, few studies have investigated the relationship between SP and RI in patients with OCD.
Keitaro Murayama +7 more
wiley +1 more source

