Results 221 to 230 of about 55,554 (301)

Editor's note. [PDF]

J Clin Monit Comput
Flick M.
europepmc   +1 more source

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

British Journal of Pharmacology, Volume 183, Issue 9, Page 1845-1859, May 2026.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim, Junhyuk Woo, Sungmin Pak, Joonho Paik, Gyu‐Sang Hong, Ji Hun Wi, Sanghee Lee, Cristina Fenollar‐Ferrer, Kyungreem Han, Young Kee Shin, Uhtaek Oh   +10 more
wiley   +1 more source

Temporal recovery in motor evoked potential during evacuation of cervical spontaneous epidural hematoma: illustrative case. [PDF]

J Neurosurg Case Lessons
Matsuoka R, Takeshima Y, Takatani T, Morisaki Y, Kim TK, Yokoyama S, Hayashi H, Matsuda R, Park YS, Kawaguchi M, Nakagawa I.   +10 more
europepmc   +1 more source

Visual phosphene perception modulated by subthreshold crossmodal sensory stimulation (vol 27, pg 4178, 2007) [PDF]

, 2007
Amedi, A, Fregni, F, Machii, K, Merabet, LB, Pascual-Leone, A, Ramos-Estebanez, C, Romei, V, Thut, G, Wagner, TA   +8 more
core  

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

British Journal of Pharmacology, Volume 183, Issue 10, Page 2307-2323, May 2026.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert, Chantal Fitterer, Sylvain Hugel, Mila Jesic, Yannick Goumon, Virgine Andry, Severine Schneider, Francois Daubeuf, Abdelfattah Faouzi, Stephane Doridot, Susruta Majumdar, Frederic Bihel, Martine Schmitt, Dominique Massotte   +13 more
wiley   +1 more source

Effects of repetitive mechanical tactile stimulation interventions with stationary and moving patterns on paired-pulse depression. [PDF]

BMC Neurosci
Watanabe H, Kojima S, Otsuru N, Onishi H.   +3 more
europepmc   +1 more source

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

British Journal of Pharmacology, Volume 183, Issue 10, Page 2324-2340, May 2026.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann, Mariana O. Popa, Karen T. Elvers, Misa Oyama, Daniel Ulrich, Marcus Hanley, Gui Jie Feng, Thomas Hathaway, William T. Ralvenius, Thomas Grampp, Dietmar Benke, John R. Atack, Hanns Ulrich Zeilhofer   +12 more
wiley   +1 more source

Compressive spontaneous spinal epidural hematoma following cervical laminoplasty and the role of multimodal neuromonitoring: a case report. [PDF]

J Spine Surg
Dhodapkar MM, Sarraj M, Mechas CA, Hoffman EM, Crum B, Freedman BA.   +5 more
europepmc   +1 more source

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

British Journal of Pharmacology, Volume 183, Issue 9, Page 2139-2165, May 2026.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi, Deniz Queisser, Alena Senn, Hannes Sigrist, Diana Kúkeľová, Lorraine Madur, Nagiua Cuomo‐Haymour, Mélisse Robert, Sophie Schmid, Adrián Portalés, Sophie Simard, Naguib Mechawar, Bastian Hengerer, Stefan Just, Christopher R. Pryce   +14 more
wiley   +1 more source

CT-Optimal Stimulation Modulates Somatosensory Processing. [PDF]

Psychophysiology
Ribeiro-Carreira A, da-Silva M, Pereira AR, Carrillo-de-la-Peña MT, Coutinho J, Sampaio A, González-Villar AJ.   +6 more
europepmc   +1 more source