Results 251 to 260 of about 326,735 (329)

GABAB Receptor: Structure, Biological Functions, and Therapy for Diseases

MedComm, Volume 6, Issue 5, May 2025.
Within the GABAergic system, GABABRs are potential therapeutic targets for dealing multiple metabolic and binge eating disorders and food addiction. Allosteric modulators and small peptides targeting GABABR signaling pathways may be developed as attractive drug candidates that avoid the side effects of agents that directly bind these receptors ...
Weijie Xie, Yuan Li, Xinyue Wang, Elena Blokhina, Evgeny Krupitsky, Marina Vetrova, Ji Hu, Ti‐Fei Yuan, Jue Chen, Hua Wang, Xiangfang Chen   +10 more
wiley   +1 more source

Persistent Spinal Pain Syndrome: A Study of Contact Heat-Evoked Potentials. [PDF]

Cureus
Lima Pessôa B, Davidovich E, Nascimento O, Hauwanga WN, McBenedict B.   +4 more
europepmc   +1 more source

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

MedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes, Patrizia Rubini, Henning Ulrich, Hai‐Yan Yin, Yong Tang   +4 more
wiley   +1 more source

Cholecystokinin neurons in the spinal trigeminal nucleus interpolaris regulate mechanically evoked predatory hunting in male mice. [PDF]

Nat Commun
Geng D, Li Y, Yang B, Zhang L, Gu H, Zhang T, Zhao Z, Liu H, Cui Q, Zheng R, Cao P, Zhang F.   +11 more
europepmc   +1 more source

An overview of the non‐procedural treatment options for peripheral neuropathic pain

Muscle &Nerve, Volume 71, Issue 5, Page 791-801, May 2025.
Abstract Peripheral neuropathic pain is common in patients with peripheral nerve injury and can significantly impact both their function and quality of life. There is a wide variety of non‐interventional treatment approaches, including pharmacologic therapy, physical/occupational therapy, modalities (therapeutic, mechanical, thermal, etc.), psychology,
Evan R. Zeldin, Adam R. Goddard, Maxwell S. Boyle, Renee L. Madathil, Erick Rosenvall, Kajri A. Majithia, Eric J. Morrison   +6 more
wiley   +1 more source

A wide-ranging review of galvanic vestibular stimulation: from its genesis to basic science and clinical applications. [PDF]

Exp Brain Res
Marchand S, Langlade A, Legois Q, Séverac Cauquil A.   +3 more
europepmc   +1 more source

Hes5⁺ astrocytes potentiate primary afferent Aδ and C fiber-mediated excitatory synaptic transmission to spinal lamina I neurons. [PDF]

Mol Brain
Kagiyama I, Uchiyama S, Tsuda M.
europepmc   +1 more source

Nerve conduction velocity in patients under longterm treatment with antiepileptic drugs [PDF]

, 1990
Berlit, Peter, Krause, Klaus-Henning
core  

Reliability of Brain Activity During a Supine Bilateral Leg Press and Association With Concurrent 3D Knee Joint Biomechanics

European Journal of Neuroscience, Volume 61, Issue 9, May 2025.
The current study established the leg press task as a reliable paradigm for investigating brain activity and concurrent knee joint kinematics. Furthermore, it identified a relationship between knee sagittal range of motion and brain activity in the right LOC and bilateral putamen, potentially reflecting enhanced sensorimotor integration and motor ...
HoWon Kim, Taylor M. Zuleger, Alexis B. Slutsky‐Ganesh, Manish Anand, Shayla M. Warren, Jed A. Diekfuss, Bryan R. Schlink, Justin L. Rush, Janet E. Simon, Gregory D. Myer, Dustin R. Grooms   +10 more
wiley   +1 more source

Temporal Dynamics of Moderate-Intensity Transcranial Static Magnetic Stimulation in Young Adults. [PDF]

J Clin Med Res
Chen PL, Cui X, Zhang Q, Zheng HD, Kong FR, Ye H, Guo JM, Cui M.   +7 more
europepmc   +1 more source