Low-frequency local field potentials and spikes in primary visual cortex convey independent visual information [PDF]
, 2008 Local field potentials (LFPs) reflect subthreshold integrative processes that complement spike train measures. However, little is yet known about the differences between how LFPs and spikes encode rich naturalistic sensory stimuli.
Belitski, A. +6 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Gain modulation of synaptic inputs by network state in auditory cortex in vivo [PDF]
, 2015 The cortical network recurrent circuitry generates spontaneous activity organized into Up (active) and Down (quiescent) states during slow-wave sleep or anesthesia.
Destexhe, Alain +4 more
core +3 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Clinical and electrophysiological correlation in patient with optic neuritis
Revista Cubana de Investigaciones Biomédicas, 2020 Introduction: Optic neuritis is a disorder frequently find in our environment. Material and methods: A descriptive and traverse study was performed in patients with diagnosis of optic neuritis, that attended to the neurophthalmology service of the ...
Lianne Alicia Chang Arraño +3 more
doaj
Estimation of Evoked Potentials Using Wavelet Transform Based Time-Frequency Adaptive Filtering [PDF]
, 1997 A time-frequency domain adaptive filtering method is presented to estimate evoked potentials. The wavelet transform is used to represent the original responses in the time-frequency domain with a discrete set of wavelet coefficients.
Chan, FHY +4 more
core +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Visual Evoked Potentials: Normative Values and Gender Differences [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: Visual evoked potentials (VEP) are used to assess the visual pathways through the optic nerves and brain. A normal VEP response to a pattern-reversal stimulus is a positive mid occipital peak that occurs at a mean latency of 100 ms. VEP
RUBY SHARMA +3 more
doaj +1 more source
Excitability of the motor cortex in patients with migraine changes with the time elapsed from the last attack [PDF]
, 2017 BACKGROUND: Motor-evoked potentials (MEPs) produced by single-pulse transcranial magnetic stimulation (TMS) of the motor cortex can be an objective measure of cortical excitability.
COPPOLA, GIANLUCA +6 more
core +1 more source