Results 31 to 40 of about 5,710 (181)

Early Addition of Evolocumab to Statin Treatment in Patients with Acute Coronary Syndrome and Multivessel Disease Undergoing Percutaneous Coronary Intervention

open access: yesReviews in Cardiovascular Medicine, 2023
Background: Evolocumab has been demonstrated to significantly reduce ischemic cardiovascular events in patients with stable coronary heart disease. However, it is currently unclear whether this benefit extends to patients with acute coronary syndrome ...
Yahao Zhang   +7 more
doaj   +1 more source

Evolocumab: rising momentum as novel antidyslipidemic drug [PDF]

open access: yes, 2017
Increased levels of low density lipoprotein cholesterol are responsible for the major cardiovascular events. Low density lipoprotein cholesterol reduction has proved to be highly effective in reducing the risk of major cardiovascular (CV) events in ...
Rimjhim Sahu   +7 more
core   +1 more source

Early effects of PCSK9 inhibitors: evolocumab versus alirocumab [PDF]

open access: yesKosin Medical Journal
Background The significance of risk modification in patients with acute coronary syndrome (ACS) is well recognized; however, the optimal timing for adminstering PCSK9 inhibitors remains unclear. Additionally, the lipid-lowering efficacy of evolocumab and
Su-Hyun Bae   +5 more
doaj   +1 more source

EXPERIENCE WITH THE USE OF EVOLOCUMAB THERAPY IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA (IN KARELIA REPUBLIC)

open access: yesЕвразийский Кардиологический Журнал, 2020
Aim: to evaluate the efficacy and safety of the use of evolocumab in patients with familial hypercholesterolemia (FH).Materials and methods: Fifteen patients with a definite FH were treated with PCSK9 inhibitors, in 11 patients with a history of CAD ...
V. A. Korneva   +2 more
doaj   +1 more source

Evolocumab and clinical outcomes in patients with cardiovascular disease [PDF]

open access: yes, 2017
Evolocumab and clinical outcomes in patients with cardiovascular ...
Robert P Giugliano (19897608)   +499 more
core   +7 more sources

Evolocumab for Early Reduction of LDL-Cholesterol Levels in Patients with Acute Coronary Syndromes (EVOPACS). [PDF]

open access: yes, 2019
BACKGROUND While guidelines recommend in-hospital initiation of high-intensity statin therapy in patients with acute coronary syndromes (ACS), low-density lipoprotein cholesterol (LDL-C) target levels are frequently not attained. Evolocumab, a rapidly
Deckarm, O.   +31 more
core   +3 more sources

Atrial Fibrillation as a Possible Adverse Reaction to Evolocumab.

open access: yes, 2021
Evolocumab is a recently FDA-approved proprotein convertase subtilisin/kexin type 9 inhibitor (PCSK9i) that reduces the risk of myocardial infarction, stroke, and coronary revascularization in individuals with established atherosclerotic cardiovascular ...
Hasan, Mustajab   +3 more
core   +1 more source

Evolocumab is Initiated in Central and Eastern Europe at Much Higher LDL-C Levels Than Recommended in Guidelines: Results from the Observational HEYMANS Study

open access: yesJournal of Cardiovascular Pharmacology and Therapeutics, 2023
Purpose: We examined clinical characteristics and low-density lipoprotein cholesterol (LDL-C) lowering in patients initiating evolocumab in real-world practice in a Central and Eastern European (CEE) cohort from the pan-European HEYMANS study.
Vladimír Blaha MUDr, CSc   +9 more
doaj   +1 more source

Real-World Insights Into Evolocumab Use in Patients With Hyperlipidemia: Canadian Analysis From the ZERBINI Study

open access: yesCJC Open, 2022
Background: The 2021 Canadian Cardiovascular Society guidelines recommend proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitor therapy in patients with atherosclerotic cardiovascular disease whose low-density lipoprotein cholesterol (LDL-C ...
Milan Gupta, MD   +10 more
doaj   +1 more source

Factorial Effects of Evolocumab and Atorvastatin on Lipoprotein Metabolism

open access: yes, 2021
Background: Monoclonal antibodies against proprotein convertase subtilisin kexin type 9 (PCSK9), such as evolocumab, lower plasma low-density lipoprotein (LDL)-cholesterol concentrations.
Burrows, Sally   +7 more
core   +1 more source

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