Results 221 to 230 of about 7,622,829 (352)

Self-Regulating Hydrogel with Reversible Optical Activity in Its Gel-to-Gel Transformation. [PDF]

J Am Chem Soc
Li J, Yin F, Wang J, Du H, Xu F, Meskers S, Li Y, Wijker S, Peng Y, Bellan R, Vantomme G, Song J, Liu CS, Meijer EW.   +13 more
europepmc   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Surface reconstruction and chemical evolution of stoichiometric layered cathode materials for lithium-ion batteries

Nature Communications, 2014
Feng Lin, Isaac M. Markus, D. Nordlund, T. Weng, M. Asta, H. Xin, M. Doeff   +6 more
semanticscholar   +1 more source

Risk of fragility fracture is aggravated during bone regeneration processes in osteoporotic sheep. [PDF]

PLoS One
Toscano-Angulo JJ, Mora-Macías J, Blázquez-Carmona P, Morgaz J, Navarrete-Calvo R, Domínguez J, Reina-Romo E.   +6 more
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Decomposing the molecular complexity and transformation of dissolved organic matter for innovative anaerobic bioprocessing. [PDF]

Nat Commun
Hu J, Liu CG, Zhang WK, Liu XW, Dong B, Wang ZD, Xie YG, Hua ZS, Liu XW.   +8 more
europepmc   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Molecular Ir-Based Coordination Compound Grafted onto Covalent Organic Framework for Efficient Photocatalytic H₂ Evolution. [PDF]

Materials (Basel)
Wu C, Zhang H, Zheng X, Ding J, Li Y, Chen F, Zhao Z.   +6 more
europepmc   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

A quantitative analysis method based on network evolution for risk factors of safety production in chemical enterprises. [PDF]

Sci Rep
Tao R, Li D, Shi H, Pang S, Lin Y, Li C.
europepmc   +1 more source