Results 271 to 280 of about 6,342,096 (314)
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Origins of life and evolution of the biosphere, 1999
We propose the existence of a relationship of stereochemical complementarity between gene sequences that code for interacting components: nucleic acid-nucleic acid, protein-protein and protein-nucleic acid. Such a relationship would impose evolutionary constraints on the DNA sequences themselves, thus retaining these sequences and governing the ...
L F, Harris +2 more
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We propose the existence of a relationship of stereochemical complementarity between gene sequences that code for interacting components: nucleic acid-nucleic acid, protein-protein and protein-nucleic acid. Such a relationship would impose evolutionary constraints on the DNA sequences themselves, thus retaining these sequences and governing the ...
L F, Harris +2 more
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On the rate of molecular evolution
Journal of Molecular Evolution, 1971There are at least two outstanding features that characterize the rate of evolution at the molecular level as compared with that at the phenotypic level. They are; (1) remarkable uniformity for each molecule, and (2) very high overall rate when extrapolated to the whole DNA content.
M, Kimura, T, Ota
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Molecular Evolution of Catalysis
Journal of Theoretical Biology, 2000In this paper, we consider the evolutionary dynamics of catalytically active species with a distinct genotype-phenotype relationship. Folding landscapes of RNA molecules serve as a paradigm for this relationship with essential neutral properties. The landscape itself is partitioned by phenotypes (realized as RNA secondary structures). To each genotype (
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The molecular evolution of trypanosomatidae
2001In the absence of a fossil record, theories relating to the evolution of protozoa have, for most of the twentieth century, been based on morphological and life cycle data despite their known limitations. However, recent advances in molecular methodology, notably the wide availability of accurate, automated DNA sequencing, have made it possible to ...
J R, Stevens +3 more
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Molecular insights into evolution
Artificial Life and Robotics, 1999The evolution of ribonucleic acid (RNA) molecules in the test tube provides a possible way to study evolutionary optimization and adaptation to the environment on time scales accessible to human observers. Diversity of genotypes, however, is prohibitive for a complete experimental recording of the process at the molecular level.
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Disciplining molecular evolution
Trends in Ecology & Evolution, 1998Molecular Evolution by W-H. Li Sinauer, 1997. £32.95 hbk (xv+487 pages) ISBN 0 87893 463 4.
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Molecular evolution and optimization
Antonie van Leeuwenhoek, 1997Microbial populations (and life) not only evolve, they optimize. The transition from a random, unorganized, lifeless Earth to the present situation, where the Earth is virtually covered with nucleic acids and diverse and complex species, required numerous molecular changes and the integration of metabolic pathways over billions of years.
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Journal of Theoretical Biology, 1992
The exciting results published by Scott & Smith (1990), Devlin et al. (1990), and Tuerk & Gold (1990) in Science; Cwirla et al., in the Proceedings of the National Academy of Sciences of the U.S.A. (1990) ; and Ellington & Szostak in Nature, London (1990), are the next developments in a new era in biotechnology: applied molecular evolution.
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The exciting results published by Scott & Smith (1990), Devlin et al. (1990), and Tuerk & Gold (1990) in Science; Cwirla et al., in the Proceedings of the National Academy of Sciences of the U.S.A. (1990) ; and Ellington & Szostak in Nature, London (1990), are the next developments in a new era in biotechnology: applied molecular evolution.
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Molecular evolution in bacteria
Antonie van Leeuwenhoek, 1995Recent advances in microbiology and molecular biology have a unifying influence on our understanding of genetic diversity/similarity and evolutionary relationships in microorganisms. This article attempts to unify information from diverse areas such as microbiology, molecular biology, microbial physiology, clay crystal genes, metals-microbe-clay ...
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General and Comparative Endocrinology, 2001
Leptin, a hormone produced mainly by adipocytes, is involved in the regulation of food intake, metabolism, and reproduction. The objective of this study was to determine the evolutionary relationships of leptin genes. Partial nucleotide sequences of leptin were cloned and sequenced from six mammalian species: large hairy armadillo (Chaetophractus ...
C, Doyon +3 more
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Leptin, a hormone produced mainly by adipocytes, is involved in the regulation of food intake, metabolism, and reproduction. The objective of this study was to determine the evolutionary relationships of leptin genes. Partial nucleotide sequences of leptin were cloned and sequenced from six mammalian species: large hairy armadillo (Chaetophractus ...
C, Doyon +3 more
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