Results 281 to 290 of about 6,342,096 (314)
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The molecular evolution of development
BioEssays, 1998Morphological differences between species, from simple single-character differences to large-scale variation in body plans, can be traced to changes in the timing and location of developmental events. This has led to a growing interest in understanding the genetic basis behind the evolution of developmental systems.
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Molecular Evolution of Proteasomes
2002Proteasomes are large, multisubunit proteases that are found, in one form or another, in all domains of life and play a critical role in intracellular protein degradation. Although they have substantial structural similarity, the proteasomes of bacteria, archaea, and eukaryotes show many differences in architecture and subunit composition. This article
Volker, C. +1 more
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Annual Review of Ecology and Systematics, 1986
Many patterns in the evolution of proteins and DNA are now well established and have been adequately reviewed in recent years (23, 37, 38, 52, 55, 61, 73). However, there are several gaps in our understanding of the process of molecular evolution, the most conspicuous of which is our ignorance of the forces responsible for most of the evolution of DNA ...
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Many patterns in the evolution of proteins and DNA are now well established and have been adequately reviewed in recent years (23, 37, 38, 52, 55, 61, 73). However, there are several gaps in our understanding of the process of molecular evolution, the most conspicuous of which is our ignorance of the forces responsible for most of the evolution of DNA ...
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Molecular Evolution of hisB Genes
Journal of Molecular Evolution, 2004The sixth and eighth steps of histidine biosynthesis are catalyzed by an imidazole glycerol-phosphate (IGP) dehydratase (EC 4.2.1.19) and by a histidinol-phosphate (HOL-P) phosphatase (EC 3.1.3.15), respectively. In the enterobacteria, in Campylobacter jejuni and in Xylella/Xanthomonas the two activities are associated with a single bifunctional ...
M. Brilli, FANI, RENATO
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Molecular evolution of proglucagon
Regulatory Peptides, 2001The vertebrate proglucagon gene encodes glucagon, and the two glucagon-like peptides GLP-1 and GLP-2. To better understand the origin and diversification of the distinct hormonal roles of the three glucagon-like sequences encoded by the proglucagon gene, we have examined the evolution of this gene.
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Molecular Evolution of Influenza Viruses
Virus Genes, 1995There are two different mechanisms by which influenza viruses might evolve: (1) Because the RNA genome of influenza viruses is segmented, new strains can suddenly be produced by reassortment, as happens, for example, during antigenic shift, creating new pandemic strains.
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Molecular imaging in oncology: Current impact and future directions
Ca-A Cancer Journal for Clinicians, 2022Martin G. Pomper, Steven P Rowe
exaly
This chapter explores molecular evolution by examining how mutations shape protein function, structure, and evolutionary relationships. It explains how conserved regions arise due to functional, structural, or ancestral gene relatedness and highlights p53 as a model for understanding mutation impacts, particularly in cancer.
Jamil Momand, Eliot Bush
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Jamil Momand, Eliot Bush
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Clinical management of metastatic colorectal cancer in the era of precision medicine
Ca-A Cancer Journal for Clinicians, 2022Josep Tabernero Caturla +2 more
exaly