Results 61 to 70 of about 1,852,937 (255)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Transcriptional profiles of the fish parasite Neoechinorhynchus agilis (Acanthocephala) emphasize energetic stress in males and high cell-division activity in females

BMC Genomics
Background Thorny-headed worms (Acanthocephala) occur worldwide in gnathostome vertebrates feeding on mandibulate arthropods. They can manipulate host behavior, accumulate heavy metals, and have lately gained economic relevance as a pest in fish ...
Camille-Sophie Cozzarolo, Alexandros Vasilikopoulos, Olivier De Thier, Laura Hagemann, Bahram Sayyaf Dezfuli, Karine van Doninck, Holger Herlyn   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Molecular Cloud Evolution III. Accretion vs. stellar feedback

, 2010
We numerically investigate the effect of feedback from the ionizing radiation heating from massive stars on the evolution of giant molecular clouds (GMCs) and their star formation efficiency (SFE).
Alan W. Watson, Ballesteros-Paredes, Brunt, Carpenter, Carroll, Caselli, Ceverino, Diaz-Miller, Dib, Elmegreen, Elmegreen, Enrique Vázquez-Semadeni, Evans, Federrath, Gazol, Gilberto C. Gómez, Hartmann, Hartmann, Heitsch, Heitsch, Hennebelle, Hennebelle, Heyer, Hillenbrand, Hillenbrand, Javier Ballesteros-Paredes, Klessen, Klessen, Klessen, Koyama, Koyama, Kravtsov, Kravtsov, Krumholz, Krumholz, Krumholz, Li, Li, Matzner, Matzner, McKee, Nakamura, Nordlund, Ostriker, Ostriker, Padoan, Padoan, Pedro Colín, Rathborne, Rosas-Guevara, Scalo, Spaans, Spezzi, Tan, Tobin, Truelove, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Wada, Wada, Wang, Whitworth, Williams, Yorke   +67 more
core   +1 more source

Dynamical Evolution of Globular Clusters in Hierarchical Cosmology [PDF]

, 2006
We probe the evolution of globular clusters that could form in giant molecular clouds within high-redshift galaxies. Numerical simulations demonstrate that the large and dense enough gas clouds assemble naturally in current hierarchical models of galaxy ...
Forbes D. A., Forte J. C., Frenk C. S., José L. Prieto, Kissler-Patig M., Lahav O., Maccio A. V., Miyamoto M., Murali C., Murali C., Murali C., Oleg Y. Gnedin, Scalo J. M., Thomas P.   +13 more
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Climate change affects the parasitism rate and impairs the regulation of genes related to oxidative stress and ionoregulation of Colossoma macropomum

Scientific Reports, 2021
Global climate change represents a critical threat to the environment since it influences organismic interactions, such as the host-parasite systems, mainly in ectotherms including fishes.
Jaqueline Custodio da Costa, Samara Silva de Souza, Jonatas da Silva Castro, Renan Diego Amanajás, Adalberto Luis Val   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Imaging the Breakdown of Molecular-Frame Dynamics through Rotational Uncoupling

, 2017
We demonstrate the breakdown of molecular-frame dynamics induced by the uncoupling of molecular rotation from electronic motion in molecular Rydberg states. We observe this non-Born-Oppenheimer regime in the time domain through photoelectron imaging of a
Bucksbaum, Philip H., Natan, Adi, Zipp, Lucas J.   +2 more
core   +1 more source

Evolutionary ecology of opsin gene sequence, expression and repertoire. [PDF]

, 2017
Linking molecular evolution to biological function is a long-standing challenge in evolutionary biology. Some of the best examples of this involve opsins, the genes that encode the molecular basis of light reception.
Owens, Gregory L, Rennison, Diana J
core   +1 more source