Results 41 to 50 of about 694,227 (269)

Enzyme-assisted high throughput sequencing of an expanded genetic alphabet at single base resolution

open access: yesNature Communications
With just four building blocks, low sequence information density, few functional groups, poor control over folding, and difficulties in forming compact folds, natural DNA and RNA have been disappointing platforms from which to evolve receptors, ligands ...
Bang Wang   +8 more
doaj   +1 more source

Experimental increase of worker diversity benefits brood production in ants

open access: yesBMC Ecology and Evolution, 2021
Background The reproductive division of labor of eusocial insects, whereby one or several queens monopolize reproduction, evolved in a context of high genetic relatedness.
Marina N. Psalti   +2 more
doaj   +1 more source

Molecular Evolution of Glycoproteins

open access: yesThe Tohoku Journal of Experimental Medicine, 1972
Glycopeptides have been systematically classified based on the carbohydrate-peptide linkages and on the structure of carbohydrate units, and the hypotheses have been proposed regarding the evolution of these glycopeptides. Of seven types of carbohydrate-peptide linkages so far established, only glucosaminylasparagine linkage evolved in the proto ...
openaire   +3 more sources

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Enhancing UV-C and perchlorate resistance in Arabidopsis thaliana through the introduction of microbial genes from hypersaline environment

open access: yesFrontiers in Microbiology
Ultraviolet (UV) radiation reaching the Earth's surface affects all living organisms. Recent reports show a trend of increasing exposure levels due to stratospheric ozone depletion and contamination.
Carolina González de Figueras   +7 more
doaj   +1 more source

Point of sampling detection of Zika virus within a multiplexed kit capable of detecting dengue and chikungunya

open access: yesBMC Infectious Diseases, 2017
Background Zika, dengue, and chikungunya are three mosquito-borne viruses having overlapping transmission vectors. They cause diseases having similar symptoms in human patients, but requiring different immediate management steps.
Ozlem Yaren   +8 more
doaj   +1 more source

Inhibition of a nutritional endosymbiont by glyphosate abolishes mutualistic benefit on cuticle synthesis in Oryzaephilus surinamensis

open access: yesCommunications Biology, 2021
Kiefer et al. sequence the metagenome of the sawtoothed grain beetle and demonstrate how its symbiont mechanistically helps the host by providing tyrosine. Providing this amino acid in the pupal stage and early adulthood supports cuticle biosynthesis and
Julian Simon Thilo Kiefer   +8 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Molecular Evolution of Paramyxoviruses.

open access: yesUirusu, 1996
We reviewed immunological relationships between paramyxoviruses and molecular evolution of paramyxoviruses. (1) paramyxoviruses are divided into two groups by the basis of the immunological relationship, i.e., parainfluenza type 1 virus group and type 2 virus group; (2) according to the NP and M proteins sequences, paramyxoviruses are divided into ...
openaire   +4 more sources

Sociality and the Rate of Molecular Evolution [PDF]

open access: yesMolecular Biology and Evolution, 2005
The molecular clock does not tick at a uniform rate in all taxa but may be influenced by species characteristics. Eusocial species (those with reproductive division of labor) have been predicted to have faster rates of molecular evolution than their nonsocial relatives because of greatly reduced effective population size; if most individuals in a ...
Bromham, L., Leys, R.
openaire   +5 more sources

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