Results 31 to 40 of about 8,690,713 (332)

DNA Polymerases Engineered by Directed Evolution to Incorporate Nonstandard Nucleotides

Frontiers in Microbiology, 2014
DNA polymerases have evolved for billions of years to accept natural nucleoside triphosphate substrates with high fidelity and to exclude closely related structures, such as the analogous ribonucleoside triphosphates. However, polymerases that can accept
Roberto eLaos, John Michael Thomson, Steven Albert Benner   +2 more
doaj   +1 more source

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved, Meghan Hesse, Jennie Cusiter, Annabel Webb, Kimberley Docking   +4 more
wiley   +1 more source

Deconstructing the geography of human impacts on species’ natural distribution

Nature Communications
It remains unknown how species’ populations across their geographic range are constrained by multiple coincident natural and anthropogenic environmental gradients.
Conor Waldock, Bernhard Wegscheider, Dario Josi, Bárbara Borges Calegari, Jakob Brodersen, Luiz Jardim de Queiroz, Ole Seehausen   +6 more
doaj   +1 more source

Genomic architecture of adaptive radiation and hybridization in Alpine whitefish

Nature Communications, 2022
In this genomic study on Alpine whitefish radiations, the authors reveal details on the genetic architecture underlying the repeated eco-morphological diversification and the role of hybridization in the evolution of endemic whitefish species.
Rishi De-Kayne, Oliver M. Selz, David A. Marques, David Frei, Ole Seehausen, Philine G. D. Feulner   +5 more
doaj   +1 more source

Systematic errors in orthology inference and their effects on evolutionary analyses

iScience, 2021
Summary: The availability of complete sets of genes from many organisms makes it possible to identify genes unique to (or lost from) certain clades. This information is used to reconstruct phylogenetic trees; identify genes involved in the evolution of ...
Paschalis Natsidis, Paschalia Kapli, Philipp H. Schiffer, Maximilian J. Telford   +3 more
doaj   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source

Evolutionary and Expression Analyses Show Co-option of khdrbs Genes for Origin of Vertebrate Brain

Frontiers in Genetics, 2018
Genes generated by whole genome duplications (WGD) can be co-opted by changing their regulation process or altering their coding proteins, which has been shown contributable to the emergence of vertebrate morphological novelties such as vertebrate ...
Su Wang, Su Wang, Qingyun Yang, Qingyun Yang, Ziyue Wang, Ziyue Wang, Shuoqi Feng, Shuoqi Feng, Hongyan Li, Hongyan Li, Dongrui Ji, Dongrui Ji, Shicui Zhang, Shicui Zhang   +13 more
doaj   +1 more source

Evolution of evolution of superbubbles [PDF]

International Astronomical Union Colloquium, 1997
AbstractIn the first place, I will summarize the evolution of our picture of the ISM over the past several decades in order to see the importance of superbubbles for ISM structure. In accordance with the progress of observations, the picture of the ISM has dramatically changed from the 1960s.
openaire   +1 more source

Stressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware, Colter K. Clayton, Fang Wang, Sedigheh Mirzaei, Kyla Shelton, Tara M. Brinkman, Victoria Willard, Katianne M. Howard Sharp, Kevin Krull, Lindsay F. Schwartz, Melissa M. Hudson, Gregory T. Armstrong, Kirsten K. Ness, Rachel T. Webster   +13 more
wiley   +1 more source

aristaless1 has a dual role in appendage formation and wing color specification during butterfly development

BMC Biology, 2023
Background Highly diverse butterfly wing patterns have emerged as a powerful system for understanding the genetic basis of phenotypic variation. While the genetic basis of this pattern variation is being clarified, the precise developmental pathways ...
Erick X. Bayala, Nicholas VanKuren, Darli Massardo, Marcus R. Kronforst   +3 more
doaj   +1 more source