Results 61 to 70 of about 8,690,713 (332)

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro   +10 more
wiley   +1 more source

Low-cost anti-mycobacterial drug discovery using engineered E. coli

open access: yesNature Communications, 2022
Whole-cell screening for Mycobacterium tuberculosis inhibitors is complicated by the pathogen’s slow growth and biocontainment requirements. Here the authors develop engineered E.
Nadine Bongaerts   +9 more
doaj   +1 more source

(Non)Parallel Evolution [PDF]

open access: yes, 2018
Parallel evolution across replicate populations has provided evolutionary biologists with iconic examples of adaptation. When multiple populations colonize seemingly similar habitats, they may evolve similar genes, traits, or functions.
Barrett, Rowan DH   +4 more
core  

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Evolutionary genomics of socially polymorphic populations of Pogonomyrmex californicus

open access: yesBMC Biology
Background Social insects vary considerably in their social organization both between and within species. In the California harvester ant, Pogonomyrmex californicus (Buckley 1867), colonies are commonly founded and headed by a single queen (haplometrosis,
Mohammed Errbii   +5 more
doaj   +1 more source

Sex-biased gene expression is repeatedly masculinized in asexual females

open access: yesNature Communications, 2019
Evolution of optimal gene expression in females is expected to be constrained by sexually-antagonistic selection on males. Here, Parker and colleagues show that gene expression has in fact become masculinized in female stick insects across five ...
Darren J. Parker   +5 more
doaj   +1 more source

Disentangling star formation and merger growth in the evolution of luminous red galaxies [PDF]

open access: yes, 2011
We introduce a novel technique for empirically understanding galaxy evolution. We use empirically determined stellar evolution models to predict the past evolution of the Sloan Digital Sky Survey (SDSS-II) Luminous Red Galaxy (LRG) sample without any a ...
Percival, Will, Tojeiro, Rita
core   +2 more sources

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

PMEL is involved in snake colour pattern transition from blotches to stripes

open access: yesNature Communications
Corn snakes are emerging models for animal colouration studies. Here, we focus on the Terrazzo morph, whose skin pattern is characterized by stripes rather than blotches. Using genome mapping, we discover a disruptive mutation in the coding region of the
Athanasia C. Tzika   +3 more
doaj   +1 more source

Spontaneous assembly of redox-active iron-sulfur clusters at low concentrations of cysteine

open access: yesNature Communications, 2021
Iron-sulfur (FeS) proteins are involved in electron transfer and CO2 fixation. Here, the authors show that FeS clusters can form spontaneously in the presence of the amino acid cysteine, in conditions similar those expected in Hadean alkaline ...
Sean F. Jordan   +9 more
doaj   +1 more source

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