Results 101 to 110 of about 4,105,755 (293)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Controlled Fuzzy Evolution Equations

, 2018
This paper is concerned with controlled fuzzy nonlinear evolution equations of the form $$\begin{aligned} u'(t) = A\,u(t) + f\Big ( t,u(t),u(\rho (t)) \Big )+B(t)c(t),\quad t\in [t_0,t_1] ; \quad u(t_0) = u_{0}. \end{aligned}$$ Where \(c(t)\in E^1\) is a control, A generate a fuzzy semigroup and \(B:[t_0,t_1]\longrightarrow \mathscr {L}(E^1 ...
Melliani, Said, El Allaoui, Abdelati, CHADLİ, Lalla Saadia   +2 more
openaire   +3 more sources

The chaotic effects in a nonlinear QCD evolution equation

Nuclear Physics B, 2016
The corrections of gluon fusion to the DGLAP and BFKL equations are discussed in a united partonic framework. The resulting nonlinear evolution equations are the well-known GLR–MQ–ZRS equation and a new evolution equation.
Wei Zhu, Zhenqi Shen, Jianhong Ruan
doaj   +1 more source

Complex Fuzzy Evolution Equation with Nonlocal Conditions

, 2017
The objective of this paper is to study the existence and uniqueness of Mild solutions for a complex fuzzy evolution equation with nonlocal conditions that accommodates the notion of fuzzy sets defined by complex-valued membership functions.
Abdelati El Allaoui, Said Melliani, Lalla Saadia Chadli   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A stochastic version of the Price equation reveals the interplay of deterministic and stochastic processes in evolution

BMC Evolutionary Biology, 2008
Background Evolution involves both deterministic and random processes, both of which are known to contribute to directional evolutionary change.
Rice Sean H
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Evolution Equations as Space-Time Operator Equations

Journal of Mathematical Analysis and Applications, 1993
The author presents the transition from the classical semigroup theory for the initial value problem \[ \dot u(t)= 2\pi i Au(t)+ f(t), \quad t>0, \qquad u(0)= u_ 0\in Y_ 1\equiv D_ 0 (A) \] with \(f\in C_ 1 (\overline {\mathbb{R}}_ +, y)\) to the so-called ``space-time evolution problem'' \[ ((D_ \nu -A)- i\nu) u= (2\pi i)^{-1} (f+ \text{sgn} (\nu ...
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Review of Some Modified Generalized Korteweg–de Vries–Kuramoto–Sivashinsky Equations (Part II)

Foundations
In part I of this work to appear in Foudations-MDPI 2024, some existence and uniqueness results for the solutions of some equations were reviewed, such as the Korteweg–de Vries equation (KdV), the Kuramoto–Sivashinsky equation (KS), the generalized ...
Marie-Thérèse Aimar, Abdelkader Intissar   +1 more
doaj   +1 more source