Results 121 to 130 of about 169,626 (311)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Approximate controllability of distributed systems by distributed controllers

open access: yesElectronic Journal of Differential Equations, 2005
Approximate controllability problem for a linear distributed control system with possibly unbounded input operator, connected in a series to another distributed system without control is investigated.
Benzion Shklyar, Vladimir Marchenko
doaj  

Mean field limits of co-evolutionary signed heterogeneous networks

open access: yesEuropean Journal of Applied Mathematics
Many science phenomena are modelled as interacting particle systems (IPS) coupled on static networks. In reality, network connections are far more dynamic.
Marios Antonios Gkogkas   +2 more
doaj   +1 more source

Analytical solutions of cylindrical and spherical dust ion-acoustic solitary waves

open access: yesResults in Physics, 2019
In the present work, employing the conventional reductive perturbation method to the field equations of an unmagnetized dusty plasma consisting of inertial ions, Boltzmann electrons and stationary dust particles in the nonplanar geometry we derived ...
Essam. R. El-Zahar, Hilmi Demiray
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Symbolic Computation of Polynomial Conserved Densities, Generalized Symmetries, and Recursion Operators for Nonlinear Differential-Difference Equations [PDF]

open access: yes, 2004
Algorithms for the symbolic computation of polynomial conserved densities, fluxes, generalized symmetries, and recursion operators for systems of nonlinear differential-difference equations are presented. In the algorithms we use discrete versions of the
Jan A. S   +15 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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