Results 71 to 80 of about 984,564 (290)

The Evolution of $\Lambda$ Black Holes in the Mini-Superspace Approximation of Loop Quantum Gravity

, 2009
Using the improved quantization technique to the mini-superspace approximation of loop quantum gravity, we study the evolution of black holes supported by a cosmological constant.
A. Ashtekar, A. DeBenedictis, A. Ghosh, C. Rovelli, C. Rovelli, J. Brannlund, M. Bojowald, S. Kloster, Z. Zhou   +8 more
core   +1 more source

Cosmic Strings in an Open Universe: Quantitative Evolution and Observational Consequences [PDF]

, 1997
The cosmic string scenario in an open universe is developed -- including the equations of motion, a model of network evolution, the large angular scale CMB temperature anisotropy, and the power spectrum of density fluctuations produced by cosmic strings ...
Avelino, P. P., Caldwell, R. R., Martins, C. J. A. P.   +2 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Leveraging rules on integrated 3D semantic city models for validating scenarios of urban evolution

Data-Centric Engineering
The process to better understand the intricate evolution of our urban territories requires combining urban data from different or concurrent instances of time to provide stakeholders with more complete views of possible evolutions of a city.
Diego Vinasco-Alvarez, John Samuel, Sylvie Servigne, Gilles Gesquière   +3 more
doaj   +1 more source

Quiescent thermal emission from neutron stars in LMXBs [PDF]

, 2015
We monitored the quiescent thermal emission from neutron stars in low-mass X-ray binaries after active periods of intense activity in x-rays (outbursts).
Aguilera, Deborah N., Pons, José A., Turlione, Anabela   +2 more
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Hydrological responses of a watershed to historical land use evolution and future land use scenarios under climate change conditions [PDF]

Hydrology and Earth System Sciences, 2008
Watershed runoff is closely related to land use but this influence is difficult to quantify. This study focused on the Chaudière River watershed (Québec, Canada) and had two objectives: (i) to quantify the influence of historical agricultural land use ...
R. Quilbé, A. N. Rousseau, J.-S. Moquet, S. Savary, S. Ricard, M. S. Garbouj   +5 more
doaj  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Spectral evolution of two-layer weak geostrophic turbulence. Part I: Typical scenarios [PDF]

Nonlinear Processes in Geophysics, 1996
Long-time evolution of large-scale geophysical flows is considered in a β-plane approximation. Motions in an infinite 2-layer model ocean are treated as a system of weakly nonlinear Rossby waves (weak geostrophic turbulence). The evolution
T. Soomere, T. Soomere
doaj