Results 121 to 130 of about 4,705,313 (296)

Vertical dynamic patterns of Vibrio spp. in the northwestern Pacific Ocean

Frontiers in Microbiology
In marine ecosystems, Vibrio species are as they facilitate nutrient cycling and impact the condition of marine life. To understand their ecological dynamics and how they adapt to various environmental situations, this study examined the vertical ...
Leihaothabam Jeeny, Leihaothabam Jeeny, Leihaothabam Jeeny, Keyi Huang, Keyi Huang, Keyi Huang, Xing Chen, Xing Chen, Xing Chen, Yan Wang, Yan Wang, Yan Wang, Shaodong Zhu, Shaodong Zhu, Shaodong Zhu, Yulin Zhang, Yulin Zhang, Yulin Zhang, Xiao-Hua Zhang, Xiao-Hua Zhang, Xiao-Hua Zhang, Xiaolei Wang, Xiaolei Wang, Xiaolei Wang   +23 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Depth shapes microbiome assembly and network stability in the Mariana Trench

Microbiology Spectrum
The Mariana Trench, a stable marine ecosystem minimally impacted by human activities, has the greatest vertical depth in the ocean. Depth gradients profoundly influence the physical, chemical, and biotic conditions in the deep oceans.
Yi Li, Jinjun Kan, Feilong Liu, Kaiyue Lian, Yantao Liang, Hongbing Shao, Andrew McMinn, Hualong Wang, Min Wang   +8 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Regulation of DMSP organosulfur cycling in ubiquitous Roseobacter marine bacteria

The EMBO Journal
Dimethylsulfoniopropionate (DMSP) catabolism by marine Roseobacters is important for global biogeochemical cycling and the climate. Many Roseobacters contain competing DMSP demethylation and cleavage pathways, but only cleavage produces the climate ...
Hui-Hui Fu, Ming-Chen Wang, Zhi-Qing Wang, Yu-Han Sang, Zhen-Kun Li, Fei-Fei Li, Jia-Rong Liu, Qi-Long Qin, Xiao-Yu Zhu, Na Wang, Jin-Jian Wan, Zhao-Jie Teng, Wei-Peng Zhang, Andrew J Gates, Chun-Yang Li, Jonathan D Todd, Yu-Zhong Zhang   +16 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A continuous evolution system for contracting the host range of bacteriophage T7. [PDF]

Sci Rep, 2020
Holtzman T, Globus R, Molshanski-Mor S, Ben-Shem A, Yosef I, Qimron U.   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A Lagrangian Snow-Evolution System for Sea-Ice Applications (SnowModel-LG): Part I-Model Description. [PDF]

J Geophys Res Oceans, 2020
Liston GE, Itkin P, Stroeve J, Tschudi M, Stewart JS, Pedersen SH, Reinking AK, Elder K.   +7 more
europepmc   +1 more source

Semantic Embedding of Petri Nets into Event-B

, 2005
We present an embedding of Petri nets into B abstract systems. The embedding is achieved by translating both the static structure (modelling aspect) and the evolution semantics of Petri nets.
Attiogbe, Christian
core   +1 more source