Results 61 to 70 of about 27,661,028 (295)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Shewanella phage encoding a putative anti-CRISPR-like gene represents a novel potential viral family
Microbiology SpectrumShewanella is a prevalent bacterial genus in deep-sea environments including marine sediments, exhibiting diverse metabolic capabilities that indicate its significant contributions to the marine biogeochemical cycles.
Hongmin Wang +16 more
doaj +1 more source
Origin and evolution of the plant immune system.
New Phytologist, 2019 Contents Summary 70 I. Introduction 70 II. Ancient associations between plants and microbes 72 III. Evolutionary dynamics of plant-pathogen interactions 74 IV. Evolutionary signature of plant-pathogen interactions 74 V.
Guan-Zhu Han
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Large language models recover scientific collaboration networks from text
Applied Network ScienceScience is a collaborative endeavor. Yet, unlike co-authorship, interactions within and across teams are seldom reported in a structured way, making them hard to study at scale.
Rathin Jeyaram +2 more
doaj +1 more source
Annual changes in the microeukaryotic community in intertidal sediments, Qingdao, China
Microbiology SpectrumMicroeukaryotic communities in intertidal sediments play an important role in maintaining ecosystem health and resilience, as they are involved in ecosystem services such as nutrient cycling, organic matter breakdown, and the support of diverse marine ...
Yan Ji +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Diversity and Ecological Potentials of Marine Viruses Inhabiting Continental Shelf Seas
Advanced ScienceViruses are critical components of all marine ecosystems. However, the role of viruses in continental shelf seas, which are usually areas of intense economic development, remain poorly characterized. Here, 62 seawater viromes from the eastern continental
Xiaoyue Guo +9 more
doaj +1 more source
Applied and Environmental MicrobiologyCholine-O-sulfate (COS) and choline are ubiquitous in the environment, and diverse bacteria catabolize them into glycine betaine for osmoprotection or as a carbon and/or nitrogen source.
Jia-Rong Liu +8 more
doaj +1 more source