Results 81 to 90 of about 4,705,313 (296)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Crp and Arc system directly regulate the transcription of NADH dehydrogenase genes in Shewanella oneidensis nitrate and nitrite respiration

Microbiology Spectrum
NADH oxidation by NADH dehydrogenases (NDHs) is crucial for feeding respiratory quinone pool and maintaining the balance of NADH/NAD+. In the respiratory model organism Shewanella oneidensis, which possesses four NDHs, the longstanding notion had been ...
Jia-Rong Liu, Zhi-Qing Wang, Fei-Fei Li, Zhen-Kun Li, Ming-Chen Wang, Na Wang, Yu An, Xiu-Lan Chen, Yu-Zhong Zhang, Hui-Hui Fu   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Global genomic diversity of temperate P2-like viruses

Communications Biology
P2-like viruses (P2Vs), temperate phages of the Peduoviridae family, possess a lysogenic lifestyle that renders traditional isolation unsuitable, hindering our understanding of their diversity and ecological roles.
Yundan Liu, Ruize Liu, Kaiyang Zheng, Ziyue Wang, Hongbing Shao, Andrew McMinn, Min Wang, Yantao Liang   +7 more
doaj   +1 more source

Healthy and moribund Zhikong scallops (Chlamys farreri) developed different viral communities during a mass mortality event

mSystems
Viral assemblages of scallops are still relatively unknown. Here, metagenomic analysis was used to study virus communities in the gut of scallops to establish the first scallop virome data set (SVD); this contains 7,447 viral operational taxonomic units.
Jiaxiang Li, Kaiyang Zheng, Wei Ding, Longfei Lu, Yantao Liang, Yao Xiong, Zhongcheng Wei, Chen Gao, Yue Su, Ziyue Wang, Xin Chen, Zhenmin Bao, Xiaoli Hu, Andrew McMinn, Min Wang   +14 more
doaj   +1 more source

Open system geometric phase based on system-reservoir joint state evolution

, 2014
The geometric phase is of fundamental interest and plays an important role in quantum information processing. However, the definition and calculation of this phase for open systems remains a problem due to the lack of agreement on generalizations of the ...
Zheng, Shi-Biao
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Tidal Evolution of a Secularly Interacting Planetary System

, 2011
In a multi-planet system, a gradual change in one planet's semi-major axis will affect the eccentricities of all the planets, as angular momentum is distributed via secular interactions.
Barnes, Brouwer, Butler, Chiang, Christa Van Laerhoven, Ferraz-Mello, Jackson, Jeffreys, Mayor, Murray, Richard Greenberg, Wu, Zhang   +12 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source