Results 131 to 140 of about 79,392 (261)

A bibliometric analysis of global research trends in adoptive cell therapy for triple negative breast cancer over the past 15 years. [PDF]

Discov Oncol
Elenien WIA, Ibrahim NA, Mohamed M, Elenien YA, Heiba M, Abouelenin O, Mahmood DA, Hussein FK.   +7 more
europepmc   +1 more source

Tectonic evolution of Afar triple junction

Bulletin de la Société Géologique de France, 1991
P. Huchon, J. M. Gaulier
openaire   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Impact of Early Diagnosis and Immunosuppressive Therapy on Giant Cell Myocarditis Outcomes: A Review. [PDF]

Life (Basel)
Kundnani NR, Kumar A, Sharma A, Mihai BVM, Diana Ardelean C, Marin-Bancila L, Valcovici M, Levai C, Iancu A, Rosca CI.   +9 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Risk Trajectory and Right Ventricular Adaptation in Selexipag-Based Triple Therapy for Pulmonary Arterial Hypertension. [PDF]

Anatol J Cardiol
Mahida K, Jagtap SR.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Author Correction: Early human occupation of Australia’s eastern seaboard

Scientific Reports
Shaun Adams, Kasih Norman, Justine Kemp, Zenobia Jacobs, Michael Costelloe, Andrew Fairbairn, Richard Robins, Errol Stock, Patrick Moss, Tam Smith, Serena Love, Tiina Manne, Kelsey M. Lowe, India Logan, Michael Manoel, Karen McFadden, Darren Burns, Thomas Dooley, Zac Falkiner, Chris Clarkson   +19 more
doaj   +1 more source

Remarkable response of metaplastic breast cancer to a novel targeted AKT inhibitor TAS-117 in a Cowden syndrome patient: a case report. [PDF]

BJC Rep
Godina E, Fernández Carcaño M, Uzunparmak B, Pepper T, Shah P, Rodon J.   +5 more
europepmc   +1 more source