Results 31 to 40 of about 144,133 (245)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Improved MOEA/D Algorithm Based on Adaptive Neighborhood Strategy [PDF]

open access: yesJisuanji gongcheng, 2019
Traditional Multi-objective Evolutionary Algorithm based on Decomposition(MOEA/D)uses the fixed neighborhood scale,which reduces the population evolution efficiency.To solve this problem,an improved algorithm based on the Adaptive Neighborhood Strategy ...
GENG Huantong,HAN Weimin,DING Yangyang,ZHOU Shansheng
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A New DG Multiobjective Optimization Method Based on an Improved Evolutionary Algorithm

open access: yesJournal of Applied Mathematics, 2013
A distribution generation (DG) multiobjective optimization method based on an improved Pareto evolutionary algorithm is investigated in this paper. The improved Pareto evolutionary algorithm, which introduces a penalty factor in the objective function ...
Wanxing Sheng   +4 more
doaj   +1 more source

Evolutionary Algorithm-Based Friction Feedforward Compensation for a Pneumatic Rotary Actuator Servo System

open access: yesApplied Sciences, 2018
The friction interference in the pneumatic rotary actuator is the primary factor affecting the position accuracy of a pneumatic rotary actuator servo system.
Ke Li   +3 more
doaj   +1 more source

Decomposition-Based Multi-Objective Evolutionary Algorithm Design Under Two Algorithm Frameworks

open access: yesIEEE Access, 2020
The development of efficient and effective evolutionary multi-objective optimization (EMO) algorithms has been an active research topic in the evolutionary computation community. Over the years, many EMO algorithms have been proposed.
Lie Meng Pang, Hisao Ishibuchi, Ke Shang
doaj   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

Classification Based on Brain Storm Optimization With Feature Selection

open access: yesIEEE Access, 2021
Classification is one of the most classic problems in machine learning. Due to the global optimization ability, evolutionary computation (EC) techniques have been successfully applied to solve many problems and the evolutionary classification model is ...
Yu Xue, Yan Zhao, Adam Slowik
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Image Noise Elimination Using Evolutionary Algorithm [PDF]

open access: yesEngineering and Technology Journal, 2005
Evolutionary algorithms like Genetic Algorithms ( GA ) and Genetic programming ( GP ) are domain - independent problem solving approaches in which computer programs are evolved to solve , or approximately solve , problems .
Matheel Abdulmunim
doaj   +1 more source

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