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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Interactive operators for evolutionary architectural design [PDF]
In this paper we explore different techniques that allow the user to direct interactive evolutionary search. Broadening interaction beyond simple evaluation increases the amount of feedback and bias a user can apply to the search. Increased feedback will
Hemberg, Erik +6 more
core +2 more sources
A New DG Multiobjective Optimization Method Based on an Improved Evolutionary Algorithm
A distribution generation (DG) multiobjective optimization method based on an improved Pareto evolutionary algorithm is investigated in this paper. The improved Pareto evolutionary algorithm, which introduces a penalty factor in the objective function ...
Wanxing Sheng +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
ETEA: A euclidean minimum spanning tree-Based evolutionary algorithm for multiobjective optimization [PDF]
© the Massachusetts Institute of TechnologyAbstract The Euclidean minimum spanning tree (EMST), widely used in a variety of domains, is a minimum spanning tree of a set of points in the space, where the edge weight between each pair of points is their ...
Yang, S +8 more
core +1 more source
Improved MOEA/D Algorithm Based on Adaptive Neighborhood Strategy [PDF]
Traditional Multi-objective Evolutionary Algorithm based on Decomposition(MOEA/D)uses the fixed neighborhood scale,which reduces the population evolution efficiency.To solve this problem,an improved algorithm based on the Adaptive Neighborhood Strategy ...
GENG Huantong,HAN Weimin,DING Yangyang,ZHOU Shansheng
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Evolutionary Demographic Algorithms
4 pages and 6 ...
Marco A. R. Erra +2 more
openaire +2 more sources
Image Noise Elimination Using Evolutionary Algorithm [PDF]
Evolutionary algorithms like Genetic Algorithms ( GA ) and Genetic programming ( GP ) are domain - independent problem solving approaches in which computer programs are evolved to solve , or approximately solve , problems .
Matheel Abdulmunim
doaj +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source

